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因心力衰竭住院的资源使用及成本:阿根廷一项多中心回顾性研究

Uso de recursos y costos de hospitalizaciones por insufi ciencia card í aca: un estudio retrospective multic é ntrico en Argentina.

作者信息

Augustovski Federico, Caporale Joaquín, Fosco Matías, Alcaraz Andrea, Diez Mirta, Thierer Jorge, Peradejordi Margarita, Pichon Riviere Andrés

机构信息

Instituto de Efectividad Clínica y Sanitaria, Buenos Aires, Argentina; Departamento de Salud Pública, Facultad de Medicina, Universidad de Buenos Aires, Argentina.

Instituto de Efectividad Clínica y Sanitaria, Buenos Aires, Argentina.

出版信息

Value Health Reg Issues. 2017 Dec;14:73-80. doi: 10.1016/j.vhri.2017.08.008. Epub 2017 Sep 17.

Abstract

OBJECTIVES

Heart failure has a great impact on health budget, mainly due to the cost of hospitalizations. Our aim was to describe health resource use and costs of heart failure admissions in three important institutions in Argentina.

METHODS

Multi-center retrospective cohort study, with descriptive and analytical analysis by subgroups of ejection fraction, blood pressure and renal function at admission. Generalized linear models were used to assess the association of independent variables to main outcomes.

RESULTS

We included 301 subjects; age 75.3±11.8 years; 37% women; 57% with depressed ejection fraction; 46% of coronary etiology. Blood pressure at admission was 129.8±29.7 mmHg; renal function 57.9±26.2 ml/min/1.73 m. Overall mortality was 7%. Average length of stay was 7.82±7.06 days (median 5.69), and was significantly longer in patients with renal impairment (8.9 vs. 8.18; p=0.03) and shorter in those with high initial blood pressure (6.08±4.03; p=0.009). Mean cost per patient was AR$68,861±96,066 (US$=8,071; 1US$=AR$8.532); 71% attributable to hospital stay, 20% to interventional procedures and 6.7% to diagnostic studies. Variables independently associated with higher costs were depressed ejection fraction, presence of valvular disease, and impaired renal function.

CONCLUSIONS

Resource use and costs associated to hospitalizations for heart failure is high, and the highest proportion is attributable to the costs related to hospital stay.

摘要

目的

心力衰竭对医疗预算有重大影响,主要是由于住院费用。我们的目的是描述阿根廷三个重要机构中因心力衰竭入院的医疗资源使用情况和费用。

方法

多中心回顾性队列研究,按入院时射血分数、血压和肾功能亚组进行描述性和分析性分析。使用广义线性模型评估自变量与主要结局的关联。

结果

我们纳入了301名受试者;年龄75.3±11.8岁;37%为女性;57%射血分数降低;46%为冠状动脉病因。入院时血压为129.8±29.7 mmHg;肾功能为57.9±26.2 ml/min/1.73 m²。总体死亡率为7%。平均住院时间为7.82±7.06天(中位数5.69),肾功能损害患者住院时间显著更长(8.9天对8.18天;p=0.03),初始血压高的患者住院时间较短(

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