Efared Boubacar, Sidibé Ibrahim S, Erregad Fatimazahra, Hammas Nawal, Chbani Laila, El Fatemi Hinde
Department of Pathology, Hassan II University Hospital, Fès, Morocco.
Faculty of Medicine and Pharmacology, Sidi Mohamed Ben Abdellah University, Fès, Morocco.
Trop Med Health. 2017 Dec 14;45:40. doi: 10.1186/s41182-017-0081-6. eCollection 2017.
Breast tuberculosis is a rare form of extrapulmonary tuberculosis with clinical and radiological misleading presentations. We report herein a retrospective study of clinicopathological features of five cases of breast tuberculosis collected at Hassan II University Hospital of Fès, Morocco, a country where tuberculosis is endemic.
The mean age was 40.6 years (range of 21-59 years). Two patients presented with abscessed lesions, and three cases presented with breast lumps with a suspicion of malignancy on imaging techniques. The diagnosis has been made on histological specimens (3 biopsy specimens, 1 excisional biopsy, and 1 lumpectomy). All patients have been successfully treated after the completion of the standard antibiotherapy.
Our current study shows that the breast is rarely affected by tuberculosis even in endemic area. The clinical presentation is often misleading, and the histopathological analysis constitutes a valuable diagnostic tool. The prognosis of breast tuberculosis is good after treatment by a standard antibiotherapy.
乳腺结核是肺外结核的一种罕见形式,其临床和影像学表现具有误导性。我们在此报告一项对摩洛哥非斯哈桑二世大学医院收集的5例乳腺结核病例的临床病理特征的回顾性研究,摩洛哥是结核病的高发国家。
平均年龄为40.6岁(范围为21 - 59岁)。2例患者表现为脓肿性病变,3例表现为乳腺肿块,影像学检查怀疑为恶性。诊断基于组织学标本(3例活检标本、1例切除活检和1例肿块切除术)。所有患者在完成标准抗结核治疗后均成功治愈。
我们目前的研究表明,即使在结核病高发地区,乳腺也很少受到结核感染。临床表现常常具有误导性,组织病理学分析是一种有价值的诊断工具。经标准抗结核治疗后,乳腺结核的预后良好。