Ozmen Caglar, Deniz Ali, Deveci Onur S, Cagliyan Caglar E, Celik Aziz I, Yildiz İbrahim, Yildiz Pinar Ö, Demir Mesut, Kanadasi Mehmet
Kahramanmaras Pazarc?k State Hospital, Department of Cardiology, .
Clin Invest Med. 2017 Dec 17;40(6):E219-E227. doi: 10.25011/cim.v40i6.29122.
Tenascin-C (TN-C) and amino-terminal fragment of the B-type natriuretic peptide (NT-proBNP) are the important predictors in prognosis of heart failure (HF). The aim of this study was to analyze the relationship of TN-C and NT-proBNP levels with the frequency and severity of ventricular arrhythmia.
Our study included 107 HF patients with EF < 45%. According to Holter analysis, the patients were divided into two groups as malignant arrhythmia group (n=29) with Lown Class 4a and 4b arrhythmia and benign arrhythmia group(n=78) with Lown Class 0-3b arrhythmia. The groups were compared with respect to levels of TN-C and NT-proBNP. The relationship of TN-C and NT-proBNP levels with frequency of ventricular premature beat (VPB) was also analyzed.
NT-proBNP (5042.1±1626 versus 1417.1±1711.6 pg/ml) and TN-C (1089±348.6 versus 758.5±423.9 ng/ml) levels were significantly higher in the malignant arrhythmia group than that of the benign arrhythmia group (p.
腱生蛋白-C(TN-C)和B型利钠肽氨基末端片段(NT-proBNP)是心力衰竭(HF)预后的重要预测指标。本研究旨在分析TN-C和NT-proBNP水平与室性心律失常的频率和严重程度之间的关系。
我们的研究纳入了107例射血分数(EF)<45%的HF患者。根据动态心电图分析,将患者分为两组,即伴有洛恩4a级和4b级心律失常的恶性心律失常组(n = 29)和伴有洛恩0-3b级心律失常的良性心律失常组(n = 78)。比较两组患者的TN-C和NT-proBNP水平。还分析了TN-C和NT-proBNP水平与室性早搏(VPB)频率的关系。
恶性心律失常组的NT-proBNP水平(5042.1±1626对1417.1±1711.6 pg/ml)和TN-C水平(1089±348.6对758.5±423.9 ng/ml)显著高于良性心律失常组(p......(原文此处不完整)