Xiang Hui, Wu Guangyong, Ouyang Jia, Liu Ruen
Department of Neurosurgery, Jiangxi People's Hospital, Nanchang, People's Republic of China.
Department of Neurosurgery, Peking University People's Hospital, Beijing, People's Republic of China.
World Neurosurg. 2018 Mar;111:e335-e339. doi: 10.1016/j.wneu.2017.12.051. Epub 2017 Dec 16.
To compare the efficacy and complications of microvascular decompression (MVD) by complete neuroendoscopy versus microscopy for 213 cases of trigeminal neuralgia (TN).
Between January 2014 and January 2016, 213 patients with TN were randomly assigned to the neuroendoscopy (n = 105) or microscopy (n = 114) group for MVD via the suboccipital retrosigmoid approach. All procedures were performed by the same neurosurgeon. Follow-up was conducted by telephone interview. Statistical data were analyzed with the chi-square test, and a probability (P) value of ≤0.05 was considered statistically significant. Chi-square test was conducted using SAS 9.4 software (SAS Institute, Cary, North Carolina, USA).
There were no statistical differences between the 2 groups in pain-free condition immediately post procedure, pain-free condition 1 year post procedure, hearing loss, facial hypoesthesia, transient ataxia, aseptic meningitis, intracranial infections, and herpetic lesions of the lips. There were no instances of death, facial paralysis, cerebral hemorrhage, or cerebrospinal fluid leakage in either group.
There were no significant differences in the cure rates or incidences of surgical complications between neuroendoscopic and microscopic MVD.
比较完全神经内镜与显微镜下微血管减压术(MVD)治疗213例三叉神经痛(TN)的疗效及并发症。
2014年1月至2016年1月,213例TN患者通过枕下乙状窦后入路随机分为神经内镜组(n = 105)和显微镜组(n = 114)行MVD。所有手术均由同一位神经外科医生完成。通过电话随访。采用卡方检验分析统计数据,概率(P)值≤0.05被认为具有统计学意义。使用SAS 9.4软件(美国北卡罗来纳州卡里市SAS研究所)进行卡方检验。
两组术后即刻无痛状态、术后1年无痛状态、听力丧失、面部感觉减退、短暂性共济失调、无菌性脑膜炎、颅内感染及唇部疱疹性病变方面无统计学差异。两组均无死亡、面瘫、脑出血或脑脊液漏病例。
神经内镜与显微镜下MVD的治愈率及手术并发症发生率无显著差异。