Liu Jiayu, Wu Guangyong, Xiang Hui, Liu Ruen, Li Fang, Hei Bo, Qian Weiqiang, Song Haidong, Liu Zhi
Department of Neurosurgery, Peking University People's Hospital, Beijing, China.
Department of Neurosurgery, The Hospital of Shunyi District Beijing, Beijing, China.
Front Neurol. 2020 Dec 21;11:584224. doi: 10.3389/fneur.2020.584224. eCollection 2020.
To explore the clinical characteristics of patients with recurrent trigeminal neuralgia (TN) and the experience of microvascular decompression (MVD) in the treatment of such patients. We retrospectively analyzed clinical data, imaging examination results, surgical methods, and treatment efficacies in 127 patients with recurrent typical TN from January 2005 to December 2014. The age of the recurrent group was higher than that of the non-recurrent group ( < 0.05). The duration of pain before the first MVD procedure was longer in the recurrent group than in the non-recurrent group ( < 0.05). Patients in the recurrent group were more likely to have compression of the trigeminal nerve by the vertebrobasilar artery (VBA) or multiple vessels than patients in the non-recurrent group ( < 0.05). A Kaplan-Meier curve showed a median pain-free survival of 12 months after the first MVD procedure. The severity of pain (preoperative visual analog scale [VAS] score) in patients with recurrence was lower than that in patients with first-onset TN ( < 0.05). Vessel compression, Teflon compression or granuloma and arachnoid adhesion were considered the main causes of recurrence. Postoperative Barrow Neurological Institute (BNI) scores in the redo MVD group were excellent ( = 2) for 69 patients (53.33%) and good ( = 3) for 46 patients (36.22%). The postoperative follow-up was 63-167 months (105.92 ± 25.66). During the follow-up, no recurrence was noted. All complications were cured or improved. Microvascular decompression (MVD) is an effective surgical method for the treatment of TN. For recurrent patients, reoperation can achieve good results.
探讨复发性三叉神经痛(TN)患者的临床特征以及微血管减压术(MVD)治疗此类患者的经验。我们回顾性分析了2005年1月至2014年12月期间127例复发性典型TN患者的临床资料、影像学检查结果、手术方法及治疗效果。复发组患者的年龄高于非复发组(P<0.05)。复发组首次MVD手术前的疼痛持续时间长于非复发组(P<0.05)。与非复发组患者相比,复发组患者更易出现椎基底动脉(VBA)或多支血管对三叉神经的压迫(P<0.05)。Kaplan-Meier曲线显示首次MVD手术后无疼痛生存期的中位数为12个月。复发患者的疼痛严重程度(术前视觉模拟量表[VAS]评分)低于初发性TN患者(P<0.05)。血管压迫、聚四氟乙烯压迫或肉芽肿及蛛网膜粘连被认为是复发的主要原因。再次MVD组术后巴罗神经学研究所(BNI)评分中,69例患者(53.33%)为优(I级),46例患者(36.22%)为良(II级)。术后随访63 - 167个月(105.92±25.66)。随访期间未发现复发。所有并发症均治愈或好转。微血管减压术(MVD)是治疗TN的一种有效手术方法。对于复发患者,再次手术可取得良好效果。