Hohenbichler Katharina, Lelotte Julie, Lhommel Renaud, Tahry Riëm El, Vrielynck Pascal, Santos Susana Ferrao
Department of Neurology.
Department of Anatomopathology.
Epileptic Disord. 2017 Dec 1;19(4):476-480. doi: 10.1684/epd.2017.0947.
Rasmussen encephalitis is a rare, devastating condition, typically presenting in childhood. Cases of adult-onset Rasmussen have also been described, but the clinical picture is less defined, rendering final diagnosis difficult. We present a case of adult-onset Rasmussen encephalitis with dual pathology, associated with focal cortical dysplasia and encephalitis. We interpreted the Rasmussen encephalitis to be caused by severe and continuous epileptic activity due to focal cortical dysplasia. The best therapeutic approach for such cases remains unclear.
拉斯穆森脑炎是一种罕见的、具有破坏性的疾病，通常在儿童期发病。也有成人发病的拉斯穆森脑炎病例的报道，但临床表现不太明确，难以做出最终诊断。我们报告一例成人发病的拉斯穆森脑炎合并双重病理改变，与局灶性皮质发育异常和脑炎相关。我们认为拉斯穆森脑炎是由局灶性皮质发育异常导致的严重持续性癫痫活动引起的。此类病例的最佳治疗方法仍不明确。
