Takashima Akiko, Takeshita Naoki, Kinoshita Toshihiko
Department of Obstetrics and Gynecology Toho University Medical Center Sakura Hospital Sakura Japan.
Reprod Med Biol. 2017 Mar 22;16(2):152-156. doi: 10.1002/rmb2.12020. eCollection 2017 Apr.
To clarify the effects of small endometriomas on in vitro fertilization (IVF) outcomes. In the present study, the potential impact of small ovarian endometriomas on the quantitative and qualitative outcomes of IVF was evaluated in the same individual.
A retrospective analysis was performed, in which 118 infertile women with unilateral endometriomas that were <40 mm in size and who underwent IVF or intracytoplasmic sperm injection were evaluated. Single frozen embryo transfer cycles were performed, with separate data collections for both the affected and the unaffected ovaries, which allowed for an evaluation of the implantation rate.
The mean antral follicular count and the number of follicular flushings, retrieved oocytes, and obtained embryos were significantly lower for the endometrioma-containing ovary than for the contralateral, intact ovary. No significant difference was observed regarding the blastocyst retrieval and good-quality blastocyst retrieval rates, pregnancy rate, and clinical pregnancy or live birth rate.
Although the patients with a small endometrioma had a decreased ovarian reserve, they had lower pregnancy rates. The decision to transfer an embryo from an endometrioma-containing ovary or from a contralateral, intact ovary also might not influence the pregnancy rate.
阐明小型子宫内膜异位囊肿对体外受精（IVF）结局的影响。在本研究中，对同一患者评估了小型卵巢子宫内膜异位囊肿对IVF定量和定性结局的潜在影响。
进行一项回顾性分析，评估118例患有单侧子宫内膜异位囊肿、囊肿大小<40 mm且接受IVF或卵胞浆内单精子注射的不孕女性。进行单胚胎冻融周期，并分别收集患侧和未患侧卵巢的数据，以便评估着床率。
与对侧完整卵巢相比，含子宫内膜异位囊肿的卵巢平均窦卵泡计数、卵泡冲洗数量、回收卵母细胞数量和获得胚胎数量均显著减少。在囊胚回收和优质囊胚回收率、妊娠率以及临床妊娠或活产率方面未观察到显著差异。
尽管患有小型子宫内膜异位囊肿的患者卵巢储备降低，但她们的妊娠率较低。从含子宫内膜异位囊肿的卵巢或对侧完整卵巢移植胚胎的决定可能也不会影响妊娠率。
