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Discontinuation of Dapoxetine Treatment in Patients With Premature Ejaculation: A 2-Year Prospective Observational Study.达泊西汀治疗早泄患者的停药情况:一项为期2年的前瞻性观察研究。
Sex Med. 2017 Jun;5(2):e99-e105. doi: 10.1016/j.esxm.2017.02.003. Epub 2017 Apr 5.
2
Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects.DA-8031(一种用于健康男性受试者早泄治疗的新型选择性5-羟色胺再摄取抑制剂)的药代动力学及耐受性
Drug Des Devel Ther. 2017 Mar 10;11:713-723. doi: 10.2147/DDDT.S126861. eCollection 2017.
3
Current and Emerging Treatments for Premature Ejaculation.早泄的当前及新出现的治疗方法
Sex Med Rev. 2015 Jul;3(3):183-202. doi: 10.1002/smrj.49. Epub 2015 Oct 8.
4
The design and methodology of premature ejaculation interventional studies.早泄干预研究的设计与方法
Transl Androl Urol. 2016 Aug;5(4):508-25. doi: 10.21037/tau.2016.03.28.
5
Emerging and investigational drugs for premature ejaculation.早泄的新型和研究性药物。
Transl Androl Urol. 2016 Aug;5(4):487-501. doi: 10.21037/tau.2016.04.02.
6
Patient reported outcomes in the assessment of premature ejaculation.早泄评估中的患者报告结局
Transl Androl Urol. 2016 Aug;5(4):470-4. doi: 10.21037/tau.2016.05.04.
7
On-demand Modafinil Improves Ejaculation Time and Patient-reported Outcomes in Men With Lifelong Premature Ejaculation.按需服用莫达非尼可改善终生早泄男性的射精时间及患者报告结局。
Urology. 2016 Aug;94:139-42. doi: 10.1016/j.urology.2016.04.036. Epub 2016 May 2.
8
Incidence and Prevalence of Sexual Dysfunction in Women and Men: A Consensus Statement from the Fourth International Consultation on Sexual Medicine 2015.女性和男性性功能障碍的发病率与患病率:2015年第四届国际性医学咨询会议的共识声明
J Sex Med. 2016 Feb;13(2):144-52. doi: 10.1016/j.jsxm.2015.12.034.
9
Definitions of Sexual Dysfunctions in Women and Men: A Consensus Statement From the Fourth International Consultation on Sexual Medicine 2015.女性和男性性功能障碍的定义:2015年第四届国际性医学咨询会议的共识声明
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Current Pharmacological Management of Premature Ejaculation: A Systematic Review and Meta-analysis.早泄的当前药理学管理:系统评价和荟萃分析。
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早泄:挑战新旧概念

Premature ejaculation: challenging new and the old concepts.

作者信息

Kalejaiye Odunayo, Almekaty Khaled, Blecher Gideon, Minhas Suks

机构信息

Department of Andrology, University College London Medical School, London, W1G 8PH, UK.

Urology Department, University of Tanta, Tanta, Egypt.

出版信息

F1000Res. 2017 Dec 4;6:2084. doi: 10.12688/f1000research.12150.1. eCollection 2017.

DOI:10.12688/f1000research.12150.1
PMID:29259775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5717471/
Abstract

Premature ejaculation remains a difficult condition to manage for patients, their partners, and the clinician. Whilst prevalence rates are estimated to be 20-40%, determining a diagnosis of premature ejaculation is difficult, as the definition remains both subjective and ill-defined in the clinical context. As our understanding of the ejaculatory pathway has improved, new opportunities to treat the condition have evolved with mixed results. In this review, we explore some of these controversies surrounding the aetiology, diagnosis, and treatment of this condition and discuss potential novel therapeutic options.

摘要

早泄对于患者、其伴侣以及临床医生而言,仍然是一种难以处理的病症。虽然据估计患病率为20%-40%,但早泄的诊断却很困难,因为在临床环境中,其定义既主观又不明确。随着我们对射精途径理解的提高,治疗该病症的新机会不断涌现,但结果好坏参半。在这篇综述中,我们探讨了围绕该病症病因、诊断和治疗的一些争议,并讨论了潜在的新型治疗选择。