Yazar Fatih Mehmet, Karaağaç Mustafa, İşler Ali, Bülbüloğlu Ertan, Ezberci Fikret
Department of General Surgery, Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey.
Department of Pathology, Sütçü İmam University School of Medicine, Kahramanmaraş, Turkey.
Turk J Surg. 2017 Dec 1;33(4):243-247. doi: 10.5152/turkjsurg.2017.3574. eCollection 2017.
To evaluate the clinical characteristics of a patient operated for water-clear cell adenoma and to discuss these in the light of relevant literature.
PubMed and Google Scholar were searched to identify articles related to water-clear cell adenoma using the following keywords: parathyroid tissue, parathyroid gland, parathyroid cells, parathyroid adenoma, parathyroid hyperplasia, water-clear-cell, and water clear cell. The search included case reports, review articles, and original articles that had been published between January 1990 and November 2014 without any restrictions on language. All articles that contained information on the study population and treatment related data were identified and retrieved. In addition, an evaluation was of a case of a 47-year-old male patient with PHC who was treated at our clinic was conducted.
A total of 19 patients, including our new case, (age range: 18 to 81 years, mean±SD: 57.47±16.31 years) were included in the analysis. Eleven patients were female. Information about adenoma location was available from studies involving 17 patients and they indicated the following distribution of locations: left inferior (n=10), right superior (n=4). When preoperative imaging methods were examined, a false negative result was given by ultrasonography in 28.5% of patients and only 57.1% were positive on scintigraphy. Concomitant thyroid papillary carcinoma was determined in 1 patient. The mean tissue dimensions were 3.47±1.73 cm (range, 0.8-6.8 cm).
Water-clear cell adenoma, which shows similar clinical characteristics to other parathyroid adenomas, is an uncommon cause of hyperparathyroidism.
评估接受透明细胞腺瘤手术患者的临床特征，并结合相关文献进行讨论。
通过PubMed和谷歌学术搜索，使用以下关键词查找与透明细胞腺瘤相关的文章：甲状旁腺组织、甲状旁腺、甲状旁腺细胞、甲状旁腺腺瘤、甲状旁腺增生、透明细胞。搜索范围包括1990年1月至2014年11月发表的病例报告、综述文章和原始文章，对语言无任何限制。识别并检索所有包含研究人群信息和治疗相关数据的文章。此外，对在我们诊所接受治疗的一名47岁原发性甲状旁腺功能亢进男性患者的病例进行了评估。
包括我们的新病例在内，共有19例患者（年龄范围：18至81岁，平均±标准差：57.47±16.31岁）纳入分析。11例为女性。17例患者的研究提供了腺瘤位置信息，其显示出以下位置分布：左下（n = 10），右上（n = 4）。检查术前成像方法时，超声检查在28.5%的患者中给出假阴性结果，而闪烁扫描仅57.1%为阳性。1例患者同时患有甲状腺乳头状癌。组织平均尺寸为3.47±1.73 cm（范围，0.8 - 6.8 cm）。
透明细胞腺瘤与其他甲状旁腺腺瘤具有相似的临床特征，是甲状旁腺功能亢进的罕见病因。
