酒精性亚急性脑病伴癫痫发作（SESA）表现为局灶性非惊厥性癫痫持续状态。
Subacute Encephalopathy With Seizures in Alcoholics (SESA) Presenting as Focal Nonconvulsive Status Epilepticus.
作者信息
Kaplan Peter W, Billnitzer Andrew, Fernández-Torre José Luis
机构信息
1 Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
2 Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
出版信息
Clin EEG Neurosci. 2018 Nov;49(6):414-416. doi: 10.1177/1550059417747435. Epub 2017 Dec 20.
PURPOSE
To acquaint readers with the underrecognized subacute encephalopathy with seizures in chronic alcoholics (SESA) that has more recently been associated with different types of status epilepticus.
METHODS
Case reports and review of the literature on SESA and nonconvulsive status epilepticus (NCSE).
RESULTS
Two cases: one with alternating bifrontoparietal NCSE, and one with focal, confusional NCSE, with imaging and EEG correlates.
CONCLUSION
Underrecognized SESA may present as NCSE with focal clinical, EEG and reversible diffusion-weighted MRI abnormalities, warranting expedited diagnosis and antiseizure treatment to minimize morbidity.
目的
使读者了解慢性酒精中毒患者中未被充分认识的伴有癫痫发作的亚急性脑病（SESA），该疾病最近与不同类型的癫痫持续状态相关。
方法
关于SESA和非惊厥性癫痫持续状态（NCSE）的病例报告及文献综述。
结果
两例病例：一例为双侧额顶叶交替性NCSE，另一例为局灶性、意识模糊性NCSE，并伴有影像学和脑电图相关性表现。
结论
未被充分认识的SESA可能表现为伴有局灶性临床、脑电图及可逆性扩散加权磁共振成像异常的NCSE，需要快速诊断和抗癫痫治疗以将发病率降至最低。
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