• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

SCP4: A Small Nuclear Phosphatase Having a Big Effect on FoxOs in Gluconeogenesis.

作者信息

Dong X Charlie

机构信息

Department of Biochemistry and Molecular Biology, Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN

出版信息

Diabetes. 2018 Jan;67(1):23-25. doi: 10.2337/dbi17-0042.

DOI:10.2337/dbi17-0042
PMID:29263168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5741148/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684c/5741148/108149030959/dbi170042f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684c/5741148/108149030959/dbi170042f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684c/5741148/108149030959/dbi170042f1.jpg

相似文献

1
SCP4: A Small Nuclear Phosphatase Having a Big Effect on FoxOs in Gluconeogenesis.SCP4：一种对糖异生过程中的FoxO蛋白有重大影响的小核磷酸酶。
Diabetes. 2018 Jan;67(1):23-25. doi: 10.2337/dbi17-0042.
2
SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation.SCP4通过FoxO1/3a去磷酸化促进糖异生作用。
Diabetes. 2018 Jan;67(1):46-57. doi: 10.2337/db17-0546. Epub 2017 Aug 29.
3
Glucose and fructose-6-phosphatase cycling by rat hepatocytes at gluconeogenesis.大鼠肝细胞在糖异生过程中的葡萄糖与6-磷酸果糖磷酸酶循环
Acta Univ Carol Med (Praha). 1981;27(7-8):477-90.
4
GdCl3 reduces hyperglycaemia through Akt/FoxO1-induced suppression of hepatic gluconeogenesis in Type 2 diabetic mice.氯化钆通过 Akt/FoxO1 诱导抑制 2 型糖尿病小鼠肝糖异生降低血糖。
Clin Sci (Lond). 2014 Jul;127(2):91-100. doi: 10.1042/CS20130670.
5
Studies on experimental hypotrophy in the rat. II. Development of some liver enzymes of gluconeogenesis.
Biol Neonate. 1971;18(1):58-65. doi: 10.1159/000240346.
6
Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor.吴茱萸生物碱通过激活组成型雄烷受体抑制糖异生和脂肪生成。
Biochim Biophys Acta. 2016 Sep;1859(9):1100-1111. doi: 10.1016/j.bbagrm.2015.10.001. Epub 2015 Oct 8.
7
Type I neuregulin1α is a novel local mediator to suppress hepatic gluconeogenesis in mice.Ⅰ型神经调节蛋白 1α 是一种新型的局部介质，可抑制小鼠的肝糖异生。
Sci Rep. 2017 Feb 20;7:42959. doi: 10.1038/srep42959.
8
Glycolytic and gluconeogenic enzyme levels in pre- and postnatal pigs.
Am J Physiol. 1971 May;220(5):1297-302. doi: 10.1152/ajplegacy.1971.220.5.1297.
9
[Effect of zenkor on the amount of glucose and activity of gluconeogenesis enzymes in carp's (Cyprinus carpio L.) tissues at different temperatures].
Ukr Biokhim Zh (1999). 2004 May-Jun;76(3):110-3.
10
MicroRNA-451 Negatively Regulates Hepatic Glucose Production and Glucose Homeostasis by Targeting Glycerol Kinase-Mediated Gluconeogenesis.微小RNA-451通过靶向甘油激酶介导的糖异生负向调节肝脏葡萄糖生成和葡萄糖稳态。
Diabetes. 2016 Nov;65(11):3276-3288. doi: 10.2337/db16-0166. Epub 2016 Aug 5.

本文引用的文献

1
SCP4 Promotes Gluconeogenesis Through FoxO1/3a Dephosphorylation.SCP4通过FoxO1/3a去磷酸化促进糖异生作用。
Diabetes. 2018 Jan;67(1):46-57. doi: 10.2337/db17-0546. Epub 2017 Aug 29.
2
Regulation of hepatic glucose metabolism in health and disease.健康与疾病状态下肝脏葡萄糖代谢的调节
Nat Rev Endocrinol. 2017 Oct;13(10):572-587. doi: 10.1038/nrendo.2017.80. Epub 2017 Jul 21.
3
The nuclear phosphatase SCP4 regulates FoxO transcription factors during muscle wasting in chronic kidney disease.核磷酸酶SCP4在慢性肾病肌肉消耗过程中调节FoxO转录因子。
Kidney Int. 2017 Aug;92(2):336-348. doi: 10.1016/j.kint.2017.02.031. Epub 2017 May 12.
4
AKT/PKB Signaling: Navigating the Network.AKT/蛋白激酶B信号传导：探索该网络
Cell. 2017 Apr 20;169(3):381-405. doi: 10.1016/j.cell.2017.04.001.
5
Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.靶向肝脏葡萄糖代谢治疗2型糖尿病。
Nat Rev Drug Discov. 2016 Nov;15(11):786-804. doi: 10.1038/nrd.2016.151. Epub 2016 Aug 12.
6
Human SCP4 is a chromatin-associated CTD phosphatase and exhibits the dynamic translocation during erythroid differentiation.人类SCP4是一种与染色质相关的CTD磷酸酶，在红细胞分化过程中表现出动态易位。
J Biochem. 2016 Aug;160(2):111-20. doi: 10.1093/jb/mvw018. Epub 2016 Feb 26.
7
The new biology of diabetes.糖尿病的新生物学
Diabetologia. 2015 Nov;58(11):2459-68. doi: 10.1007/s00125-015-3722-5. Epub 2015 Aug 7.
8
FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.FoxO1整合了胰岛素对肝脏葡萄糖生成和葡萄糖利用的直接和间接作用。
Nat Commun. 2015 May 12;6:7079. doi: 10.1038/ncomms8079.
9
Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.肝脏脂肪生成与葡萄糖生成的综合调控需要FoxO转录因子。
Nat Commun. 2014 Oct 13;5:5190. doi: 10.1038/ncomms6190.
10
C-terminal domain (CTD) small phosphatase-like 2 modulates the canonical bone morphogenetic protein (BMP) signaling and mesenchymal differentiation via Smad dephosphorylation.C 末端结构域（CTD）小磷酸酶样 2 通过 Smad 去磷酸化调节经典骨形态发生蛋白（BMP）信号传导和间充质分化。
J Biol Chem. 2014 Sep 19;289(38):26441-26450. doi: 10.1074/jbc.M114.568964. Epub 2014 Aug 6.