Watanabe Yasutaka, Kawabata Yoshinori, Iwai Yuki, Kudo Fumiaki, Kawamura Rumi, Miwa Chihiro, Nagai Yoshiaki, Koyama Shinichiro
Division of Pulmonary Medicine Saitama Medical Center Jichi Medical University Omiya City Saitama Japan.
Division of Diagnostic Pathology Saitama Prefectural Cardiovascular and Respiratory Center Kumagaya City Saitama Japan.
J Gen Fam Med. 2017 May 8;18(6):411-413. doi: 10.1002/jgf2.80. eCollection 2017 Dec.
A 29-year-old man presented with sputum and cough, which were pointed out by his neighbors. A high-resolution chest computed tomography scan showed well-defined multiple centrilobular nodules and a tree-in-bud pattern. Chest auscultation revealed coarse crackles. He did not report any nasal sinus symptoms. We subsequently performed a video-assisted lung biopsy; the specimen confirmed diffuse panbronchiolitis. Subsequently, sinusitis was confirmed by an otolaryngologist. His symptoms gradually improved following treatment with erythromycin. We report a case of early-stage diffuse panbronchiolitis in a young patient, with multiple intralobular nodules, no bronchiectasis, and a good clinical course.
一名29岁男性因邻居指出其有咳痰和咳嗽症状前来就诊。高分辨率胸部计算机断层扫描显示有边界清晰的多个小叶中心性结节及树芽征。胸部听诊闻及粗湿啰音。他未报告任何鼻窦症状。随后我们进行了电视辅助肺活检;标本证实为弥漫性泛细支气管炎。随后耳鼻喉科医生确诊为鼻窦炎。经红霉素治疗后,他的症状逐渐改善。我们报告一例年轻患者的早期弥漫性泛细支气管炎病例,有多个小叶内结节,无支气管扩张,且临床病程良好。