Lakie M, Mutch W J
Department of Biology and Preclinical Medicine, University of St Andrews, Fife, UK.
J Neurol Neurosurg Psychiatry. 1989 Mar;52(3):392-4. doi: 10.1136/jnnp.52.3.392.
Finger tremor was investigated in 20 patients (age range 54-88 yr) diagnosed as suffering from idiopathic Parkinson's disease and six controls of a similar age and no known neurological abnormality. In nine of the patients tremor was not clinically obvious. When the tremor of these patients was recorded immediately after voluntary movement and subjected to instrumental analysis there were consistently observable differences from the controls. Such analysis may have diagnostic potential when there is clinical uncertainty. Surface EMG recordings were obtained from four patients. One patient had a large resting tremor with obvious reciprocating activity in flexors and extensors; in the others who had no symptomatic tremor there was reciprocating activity only after movement, and this died away in a few seconds as the induced tremor disappeared.
对20名被诊断患有特发性帕金森病的患者（年龄范围54 - 88岁）以及6名年龄相仿且无已知神经学异常的对照者进行了手指震颤研究。在这些患者中，有9名患者的震颤在临床上并不明显。当在这些患者自愿运动后立即记录其震颤并进行仪器分析时，发现与对照组始终存在可观察到的差异。当临床诊断存在不确定性时，这种分析可能具有诊断潜力。从4名患者身上获取了表面肌电图记录。1名患者有明显的静息性震颤，屈肌和伸肌有明显的往复活动；在其他没有症状性震颤的患者中，只有在运动后才有往复活动，并且随着诱发震颤的消失，这种活动在几秒钟内就消失了。
