关于触发受体表达分子-1（TREM-1）在支架内再狭窄发展过程中的表达及作用的数据。
Data on the expression and role of TREM-1 in the development of in-stent restenosis.
作者信息
Wang Fang, Li Chang, Ding Feng Hua, Shen Ying, Gao Jie, Liu Zhu Hui, Chen Jia Wei, Zhang Rui Yan, Shen Wei Feng, Wang Xiao Qun, Lu Lin
机构信息
Department of Cardiology, RuiJin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, PR China.
Institute of Cardiovascular Diseases, Shanghai Jiao-Tong University School of Medicine, Shanghai, PR China.
出版信息
Data Brief. 2017 Nov 22;16:604-607. doi: 10.1016/j.dib.2017.11.065. eCollection 2018 Feb.
The data presented in this article are related to the research article entitled "Increased serum TREM-1 level is associated with in-stent restenosis, and activation of TREM-1 promotes inflammation, proliferation and migration in vascular smooth muscle cells" (Wang et al., 2017) [1], which demonstrated that TREM-1 is expressed on vascular smooth cells (VSMCs) and promotes inflammation, proliferation and migration in cultured VSMCs. In this dataset, the expression of TREM-1 in leukocytes and endothelial cells of carotid artery after ligation was evaluated. The effect of TREM-1 on stenosis was analyzed in cultured human saphenous veins (HSVs) that spontaneously undergo remodeling which involves VSMC proliferation and migration.
本文所呈现的数据与题为《血清TREM-1水平升高与支架内再狭窄相关，且TREM-1的激活促进血管平滑肌细胞的炎症、增殖和迁移》（Wang等人，2017年）[1]的研究文章相关，该文章表明TREM-1在血管平滑肌细胞（VSMC）上表达，并促进培养的VSMC中的炎症、增殖和迁移。在这个数据集中，评估了结扎后颈动脉白细胞和内皮细胞中TREM-1的表达。在自发经历涉及VSMC增殖和迁移的重塑过程的培养人隐静脉（HSV）中分析了TREM-1对狭窄的影响。
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