Department of Surgery, University of Colorado, Aurora; Department of Surgery, University of Southern California, Los Angeles.
Department of Surgery, University of Southern California, Los Angeles.
J Vasc Surg. 2018 Jan;67(1):254-261. doi: 10.1016/j.jvs.2017.07.107.
The incidence of morbidity and mortality for iliac vascular injuries in the literature are likely overestimated owing to associated injuries. Data for isolated iliac vascular injuries are very limited. No large studies have reported the incidence of morbidity for repair versus ligation of isolated iliac vein injuries.
Patients in the National Trauma Data Bank (NTDB; 2007-2012) with at least one iliac vascular injury were analyzed. Isolated iliac vessels were defined as cases with Abbreviated Injury Scale severity score of greater than 3 for extraabdominal injuries and an Organ Injury Scale grade of greater than 3 for intraabdominal injuries.
Overall, 6262 iliac vascular injuries (2809 penetrating, 3453 blunt) were identified in 271,076 patients with abdominal trauma (2.3%). There were 3379 patients (1841 penetrating, 1538 blunt) with isolated iliac vascular injuries (1.2%) and 557 patients (514 penetrating, 43 blunt) with combined iliac artery and vein injuries (0.2%). The 30-day mortality rate was 16.5% for isolated iliac vein injury, 19.3% for isolated iliac artery injury, and 48.7% for combined isolated iliac artery and vein injury. The 30-day mortality rate was 23.4% for isolated iliac vascular injuries compared with 39.0% for nonisolated iliac vascular injuries (P < .001). Patients with isolated iliac vein injuries had morbidity rates of deep venous thrombosis (repair, 14.6%; ligation, 14.1%; P = .875), pulmonary embolism (repair, 1.8%; ligation, 0.5%; P = .38), fasciotomy (repair, 9.3%; ligation, 14.6%; P = .094), amputation (repair, 1.8%; ligation, 2.6%; P = .738), acute kidney injury (repair, 5.8%; ligation, 4.7%; P = .627). Multivariate logistic regression demonstrated that ligation of isolated iliac vein injuries had an odds ratio of 2.2 for mortality compared with repair (95% confidence interval, 1.08-4.66).
Isolated iliac vascular injuries are associated with a high incidence of mortality, especially for combined venous and arterial injury, but mortality is significantly lower than in patients with nonisolated iliac vascular injuries. In patients with isolated iliac vein injuries, mortality was higher in patients who underwent ligation compared with repair; however, the rates of deep venous thrombosis, pulmonary embolism, fasciotomy, amputation, and acute kidney injury were not different between the treatment groups. These data lend credence to the assessment that repair of iliac vein injuries is preferable to ligation whenever feasible.
由于相关损伤,文献中髂血管损伤的发病率和死亡率可能被高估。孤立性髂血管损伤的数据非常有限。没有大型研究报告过修复与结扎孤立性髂静脉损伤的发病率。
对国家创伤数据库(NTDB;2007-2012 年)中至少有一处髂血管损伤的患者进行分析。孤立性髂血管定义为腹部创伤患者的简明损伤分级(Abbreviated Injury Scale)严重程度评分大于 3 分,腹部损伤器官损伤分级(Organ Injury Scale)大于 3 分。
在 271076 例腹部创伤患者(2.3%)中,共发现 6262 例(2809 例穿透伤,3453 例钝器伤)髂血管损伤。3379 例(1841 例穿透伤,1538 例钝器伤)患者为孤立性髂血管损伤(1.2%),557 例(514 例穿透伤,43 例钝器伤)患者为合并性髂动静脉损伤(0.2%)。孤立性髂静脉损伤的 30 天死亡率为 16.5%,孤立性髂动脉损伤的 30 天死亡率为 19.3%,合并性孤立性髂动静脉损伤的 30 天死亡率为 48.7%。孤立性髂血管损伤的 30 天死亡率为 23.4%,而非孤立性髂血管损伤的 30 天死亡率为 39.0%(P<.001)。孤立性髂静脉损伤患者的深静脉血栓形成(修复,14.6%;结扎,14.1%;P=0.875)、肺栓塞(修复,1.8%;结扎,0.5%;P=0.38)、筋膜切开术(修复,9.3%;结扎,14.6%;P=0.094)、截肢(修复,1.8%;结扎,2.6%;P=0.738)和急性肾损伤(修复,5.8%;结扎,4.7%;P=0.627)的发病率相似。多变量逻辑回归显示,与修复相比,结扎孤立性髂静脉损伤的死亡率比值比为 2.2(95%置信区间,1.08-4.66)。
孤立性髂血管损伤的死亡率很高,尤其是合并动静脉损伤时,但与非孤立性髂血管损伤患者相比,死亡率明显较低。在孤立性髂静脉损伤患者中,结扎组的死亡率高于修复组;然而,两组的深静脉血栓形成、肺栓塞、筋膜切开术、截肢和急性肾损伤的发生率无差异。这些数据支持这样一种评估,即只要有可能,修复髂静脉损伤优于结扎。