Program in Biotechnology, Montgomery College, 20200 Observation Drive, Germantown, MD 20876, USA.
Biomolecular Labeling Laboratory, National Institute of Standards and Technology and Institute for Bioscience and Biotechnology Research, University of Maryland, 9600 Gudelsky Drive, Rockville, MD 20850, USA.
Trends Microbiol. 2018 Mar;26(3):172-174. doi: 10.1016/j.tim.2017.12.001.
Chromosomal DNA replication starts at a specific region called an origin of replication. Until recently, all organisms were thought to require origins to replicate their chromosomes. It was recently discovered that some archaeal species do not utilize origins of replication under laboratory growth conditions.
染色体 DNA 复制从一个称为复制起点的特定区域开始。直到最近,人们一直认为所有生物都需要起点才能复制它们的染色体。最近发现,一些古菌物种在实验室生长条件下不利用复制起点。