润滑眼药水对视网膜光学相干断层扫描成像的影响。
The effect of lubricating eye drops on optical coherence tomography imaging of the retina.
作者信息
Ghazi Nicola G, Much Jason W
机构信息
University of Virginia.
出版信息
Digit J Ophthalmol. 2009 May 30;15(2):24-26. doi: 10.5693/djo.01.2009.006. eCollection 2009.
INTRODUCTION
The goal of this study was to examine the potential value of corneal lubrication in improving the quality of optical coherence tomography (OCT) imaging of the retina.
MATERIALS AND METHODS
This study is a consecutive series of 13 eyes of 11 patients in whom repeated attempts at OCT imaging failed to yield a good quality study despite the absence of significant media opacity or inadequate pupil dilation. Immediately following several poor quality scans, each eye received lubricating eye drops. The quality of images before and after the administration of drops was assessed.
RESULTS
A statistically significant improvement in OCT image quality was observed following the administration of eye drops in each case. The change in mean signal strength (SS) was from 4.35 to 6.26 (p=0.0002). The proportion of scans with erroneous edge detection decreased from 41 to 13 percent.
DISCUSSION
Lubricating drops appear to improve the quality and feasibility of OCT imaging in selected cases.
引言
本研究的目的是探讨角膜润滑在提高视网膜光学相干断层扫描（OCT）成像质量方面的潜在价值。
材料与方法
本研究为连续纳入11例患者的13只眼，尽管不存在明显的介质混浊或瞳孔散大不足，但多次尝试进行OCT成像均未能获得高质量的研究结果。在几次质量较差的扫描后，立即给每只眼滴入润滑眼药水。评估滴眼药水前后图像的质量。
结果
在每种情况下，滴入眼药水后OCT图像质量均有统计学意义的改善。平均信号强度（SS）的变化从4.35变为6.26（p = 0.0002）。边缘检测错误的扫描比例从41%降至13%。
讨论
在特定情况下润滑眼药水似乎可提高OCT成像的质量和可行性。
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