Edmundson Christyn, Guidon Amanda C
Neuromuscular Division, Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
Department of Neurology, Neuromuscular Division, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts.
Semin Neurol. 2017 Dec;37(6):643-652. doi: 10.1055/s-0037-1608785. Epub 2017 Dec 21.
Neuromuscular disorders may present and progress differently in women than in men. During pregnancy, medication adjustment, hormonal effects, and other alterations in physiology may influence the manifestation of a variety of neuromuscular disorders. The expression of existing conditions may change; previously asymptomatic conditions may be unmasked, or entirely new conditions may develop. Additionally, neuromuscular disorders and their treatments may have implications for the fetus. Such factors must be carefully considered when counseling and treating pregnant women and those considering pregnancy. This article reviews considerations specific to women and issues surrounding pregnancy in disorders of the neuromuscular junction, focal neuropathies, and acquired and inherited disorders of the nerve and muscle.
神经肌肉疾病在女性中的表现和进展可能与男性不同。在怀孕期间，药物调整、激素影响以及其他生理变化可能会影响多种神经肌肉疾病的表现。现有疾病的表现可能会改变；以前无症状的疾病可能会显现出来，或者可能会出现全新的疾病。此外，神经肌肉疾病及其治疗可能会对胎儿产生影响。在为孕妇和考虑怀孕的女性提供咨询和治疗时，必须仔细考虑这些因素。本文回顾了神经肌肉接头疾病、局灶性神经病以及获得性和遗传性神经肌肉疾病中特定于女性的注意事项以及与怀孕相关的问题。
