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用于治疗重症肌无力的开源模块化上睑下垂支撑器

Open source modular ptosis crutch for the treatment of myasthenia gravis.

作者信息

Saidi Trust, Sivarasu Sudesh, Douglas Tania S

机构信息

a Department of Human Biology , Division of Biomedical Engineering, University of Cape Town , Cape Town , South Africa.

出版信息

Expert Rev Med Devices. 2018 Feb;15(2):137-143. doi: 10.1080/17434440.2018.1421455. Epub 2018 Jan 15.

Abstract

INTRODUCTION

Pharmacologic treatment of Myasthenia Gravis presents challenges due to poor tolerability in some patients. Conventional ptosis crutches have limitations such as interference with blinking which causes ocular surface drying, and frequent irritation of the eyes. To address this problem, a modular and adjustable ptosis crutch for elevating the upper eyelid in Myasthenia Gravis patients has been proposed as a non-surgical and low-cost solution.

AREAS COVERED

This paper reviews the literature on the challenges in the treatment of Myasthenia Gravis globally and focuses on a modular and adjustable ptosis crutch that has been developed by the Medical Device Laboratory at the University of Cape Town.

EXPERT COMMENTARY

The new medical device has potential as a simple, effective and unobtrusive solution to elevate the drooping upper eyelid(s) above the visual axis without the need for medication and surgery. Access to the technology is provided through an open source platform which makes it available globally. Open access provides opportunities for further open innovation to address the current limitations of the device, ultimately for the benefit not only of people suffering from Myasthenia Gravis but also of those with ptosis from other aetiologies.

摘要

引言

由于部分患者耐受性较差,重症肌无力的药物治疗面临挑战。传统的上睑下垂支撑器存在局限性,比如会干扰眨眼导致眼表干燥,且频繁刺激眼睛。为解决这一问题,已提出一种用于提升重症肌无力患者上睑的模块化可调节上睑下垂支撑器,作为一种非手术且低成本的解决方案。

涵盖领域

本文综述了全球范围内重症肌无力治疗挑战的相关文献,并重点介绍了开普敦大学医疗器械实验室研发的一种模块化可调节上睑下垂支撑器。

专家评论

这种新型医疗器械有潜力成为一种简单、有效且不引人注意的解决方案,无需药物和手术就能将下垂的上睑提升至视轴上方。通过开源平台可获取该技术,从而使其在全球范围内可用。开放获取为进一步的开放式创新提供了机会,以解决该设备当前的局限性,最终不仅造福于重症肌无力患者,也惠及其他病因导致上睑下垂的患者。

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