Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas TX, USA.
Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas TX, USA; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas TX, USA.
Mol Cell. 2017 Dec 21;68(6):1019-1021. doi: 10.1016/j.molcel.2017.12.004.
In this issue of Molecular Cell, Gutierrez et al. (2017) unravel a bacterial survival strategy that they term "density-dependent persistence" or DDP. The authors demonstrate that the majority of isogenic cells in bacterial populations survive lethal antibiotic doses once bacteria consume nutrients and enter stationary growth phase.
在本期《分子细胞》中，古铁雷斯等人（2017）揭示了一种细菌生存策略，他们称之为“密度依赖性持续存在”或 DDP。作者证明，一旦细菌消耗营养物质并进入静止生长阶段，细菌种群中大多数同基因细胞能在致死抗生素剂量下存活。
