Egorov Vladimir, Murphy Miles, Lucente Vincent, van Raalte Heather, Ephrain Sonya, Bhatia Nina, Sarvazyan Noune
Artann Laboratories, Trenton, NJ, USA.
The Institute for Female Pelvic Medicine & Reconstructive Surgery, Allentown, PA, USA.
Sex Med. 2018 Mar;6(1):39-48. doi: 10.1016/j.esxm.2017.08.002. Epub 2017 Dec 19.
Few means exist to provide quantitative and reproducible assessment of vaginal conditions from biomechanical and functional standpoints.
To develop a new approach for quantitative biomechanical characterization of the vagina.
Vaginal tactile imaging (VTI) allows biomechanical assessment of soft tissue and function along the entire length of the anterior, posterior, and lateral vaginal walls. This can be done at rest, with applied vaginal deformation, and with pelvic muscle contraction.
Data were analyzed for 42 subjects with normal pelvic floor support from an observational case-controlled clinical study. The average age was 52 years (range = 26-90 years). We introduced 8 VTI parameters to characterize vaginal conditions: (i) maximum resistance force to insertion (newtons), (ii) insertion work (millijoules), (iii) maximum stress-to-strain ratio (elasticity; kilopascals per millimeter), (iv) maximum pressure at rest (kilopascals), (v) anterior-posterior force at rest (newtons), (vi) left-right force at rest (newtons), (vii) maximum pressure at muscle contraction (kilopascals), and (viii) muscle contraction force (newtons). We observed low to moderate correlation of these parameters with subject age and no correlation with subject weight. 6 of 8 parameters demonstrated a P value less than .05 for 2 subject subsamples divided by age (≤52 vs >52 years), which means 6 VTI parameters change with age.
VTI allows biomechanical and functional characterization of the vaginal conditions that can be used for (i) understanding "normal" vaginal conditions, (ii) quantification of the deviation from normality, (iii) personalized treatment (radiofrequency, laser, or plastic surgery), and (iv) assessment of the applied treatment outcome. Egorov V, Murphy M, Lucente V, et al. Quantitative Assessment and Interpretation of Vaginal Conditions. Sex Med 2018;6:39-48.
从生物力学和功能角度对阴道状况进行定量和可重复评估的方法很少。
开发一种新的方法来对阴道进行定量生物力学特征描述。
阴道触觉成像（VTI）可对阴道前壁、后壁和侧壁全长的软组织和功能进行生物力学评估。这可以在静息状态下、施加阴道变形时以及盆底肌肉收缩时进行。
对一项观察性病例对照临床研究中42名盆底支持正常的受试者的数据进行了分析。平均年龄为52岁（范围=26 - 90岁）。我们引入了8个VTI参数来表征阴道状况：（i）插入时的最大阻力（牛顿），（ii）插入功（毫焦耳），（iii）最大应力应变比（弹性；千帕每毫米），（iv）静息时的最大压力（千帕），（v）静息时的前后向力（牛顿），（vi）静息时的左右向力（牛顿），（vii）肌肉收缩时的最大压力（千帕），以及（viii）肌肉收缩力（牛顿）。我们观察到这些参数与受试者年龄呈低至中度相关，与受试者体重无相关性。8个参数中的6个在按年龄（≤52岁与>52岁）划分的2个受试者亚组中显示P值小于0.05，这意味着6个VTI参数随年龄变化。
VTI可对阴道状况进行生物力学和功能特征描述，可用于（i）了解“正常”阴道状况，（ii）量化与正常的偏差，（iii）个性化治疗（射频、激光或整形手术），以及（iv）评估所应用治疗的效果。叶戈罗夫V、墨菲M、卢森特V等。阴道状况的定量评估与解读。性医学2018；6：39 - 48。
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