Mertz-Fairhurst E J, Schuster G S, Williams J E, Fairhurst C W
J Prosthet Dent. 1979 Dec;42(6):633-7. doi: 10.1016/0022-3913(79)90193-8.
At the present time, a trend has been shown that the progress of sealed caries is markedly slowed by sealant therapy as compared to open lesions. This fact has been substantiated by depth measurements, viable bacterial counts, standardized radiographs, and clinical observations. The radiographic and clinical observations agreed with the previously reported two parameters in confirming that (1) sealed cavities showed little or no change in depth and (2) open lesions showed a significant increase in depth as compared to sealed lesions.
目前，一种趋势已显现出来，即与开放龋损相比，封闭剂治疗能显著减缓封闭性龋的进展。这一事实已通过深度测量、活菌计数、标准化X线片以及临床观察得到证实。X线片和临床观察结果与之前报道的两个参数一致，证实了：(1) 封闭的龋洞深度几乎没有变化或无变化；(2) 与封闭性龋损相比，开放龋损的深度显著增加。
