用于立体定向神经外科手术和微电极植入的鸡蛋模型训练方案
Egg Model Training Protocol for Stereotaxic Neurosurgery and Microelectrode Implantation.
作者信息
Andreoli Lorena, Simplício Hougelle, Morya Edgard
机构信息
Neuroengineering Program, Edmond and Lily Safra International Neuroscience Institute, Santos Dumont Institute, Macaíba, Brazil.
Neuroengineering Program, Edmond and Lily Safra International Neuroscience Institute, Santos Dumont Institute, Macaíba, Brazil; Biomedical Sciences Department, State University of Rio Grande do Norte, Mossoró, Brazil; Rehabilitation Center, Anita Garibaldi Center for Education and Research in Health, Santos Dumont Institute, Macaíba, Brazil.
出版信息
World Neurosurg. 2018 Mar;111:243-250. doi: 10.1016/j.wneu.2017.12.099. Epub 2017 Dec 23.
BACKGROUND
Neuroscience research uses neurosurgery in animal models for several experimental techniques. To our knowledge, there is no published method for small animal neurosurgery training. Based on the similar thickness of chicken eggshells and mouse, rat, and some small primate skulls, here we propose an egg model training protocol for stereotaxic surgery.
MATERIALS AND METHODS
To perform training it was used a boiled egg and the same materials needed to perform stereotaxic neurosurgery in small animals.
DISCUSSION
This protocol allows trainees in neuroscience research to become familiar with the microsurgery setting and learn neurosurgery techniques, such as craniotomy drilling, dura mater removal, and electrode implantation.
CONCLUSION
Egg model suitably mimics animal neurosurgery for the replacement and sparing of animals intended for training in neurosurgical skills.
背景
神经科学研究在动物模型中使用神经外科手术进行多种实验技术。据我们所知，目前尚无已发表的小动物神经外科手术训练方法。基于鸡蛋壳与小鼠、大鼠以及一些小型灵长类动物头骨厚度相似，在此我们提出一种用于立体定向手术的鸡蛋模型训练方案。
材料与方法
为进行训练，使用了一个煮鸡蛋以及在小动物身上进行立体定向神经外科手术所需的相同材料。
讨论
该方案使神经科学研究的受训人员能够熟悉显微手术环境并学习神经外科技术，如开颅钻孔、硬脑膜切除和电极植入。
结论
鸡蛋模型能很好地模拟动物神经外科手术，可替代并节省用于神经外科技能训练的动物。
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