Jeon Yong Sun, Cho Young Kwon, Song Myung Gyu, Seo Tae-Seok, Kim Jeong Ho, Song Soon-Young, Lee Sam Yeol
Department of Radiology, Inha University Hospital, Inha University College of Medicine, Incheon, Korea.
Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150 Seongan-ro Gangdong-gu, Seoul, 134-701, Korea.
Cardiovasc Intervent Radiol. 2018 Apr;41(4):554-563. doi: 10.1007/s00270-017-1867-y. Epub 2017 Dec 26.
We aimed to evaluate the clinical efficacy and short-term clinical outcomes of Kilt technique-based endovascular aneurysm repair (EVAR) with Seal stent-grafts for abdominal aortic aneurysms (AAAs) with hostile neck anatomy (angle > 60°).
We retrospectively evaluated the pre-EVAR and follow-up computed tomography angiography findings of 24 patients (mean age 71 ± 11 years; age range 32-87 years; mean follow-up 50 ± 12 months) with hostile neck AAAs treated between 2010 and 2015. Serial change in aneurysmal neck angle was calculated using a standardized protocol. Relationships between clinical variables and outcomes were evaluated using univariate and multivariate Cox analyses and mixed-model regression. In addition, the Kaplan-Meier method was used to assess the cumulative rates of survival, endoleak, and reintervention.
The primary technical success rate (success within 24 h after EVAR) was 100% (24/24). The survival rate was 96 ± 8% at 1 month, 6 months, 1 year, and 3 years, and 87 ± 18% at 5 years. Endoleaks occurred in three patients. Four reinterventions were performed in three patients; no surgical revisions were required. Causes of post-EVAR mortality included intracerebral hemorrhage at 14 days and rhabdomyolysis at 32 months. The most remarkable change after Kilt-based EVAR was an acute decrease in the neck angle, which was observed between the pre-EVAR and first follow-up visits (at 1 month) (P = 0.001).
Kilt-based EVAR with Seal stent-grafts for AAAs with a severely angulated neck (angle > 60°) provided high technical success, low mortality, and low complication rates during short-term follow-up.
我们旨在评估基于Kilt技术的带膜支架血管腔内修复术(EVAR)联合Seal覆膜支架治疗颈部解剖结构复杂(角度>60°)的腹主动脉瘤(AAA)的临床疗效和短期临床结局。
我们回顾性评估了2010年至2015年间接受治疗的24例颈部解剖结构复杂的AAA患者(平均年龄71±11岁;年龄范围32 - 87岁;平均随访50±12个月)的EVAR术前及随访期计算机断层扫描血管造影结果。使用标准化方案计算瘤颈角度的系列变化。采用单因素和多因素Cox分析以及混合模型回归评估临床变量与结局之间的关系。此外,使用Kaplan-Meier方法评估生存、内漏和再次干预的累积发生率。
主要技术成功率(EVAR术后24小时内成功)为100%(24/24)。1个月、6个月、1年和3年时的生存率为96±8%,5年时为87±18%。3例患者发生内漏。3例患者进行了4次再次干预;无需手术翻修。EVAR术后死亡原因包括14天时的脑出血和32个月时的横纹肌溶解。基于Kilt技术的EVAR术后最显著的变化是瘤颈角度在EVAR术前与首次随访(1个月时)之间急剧减小(P = 0.001)。
基于Kilt技术的EVAR联合Seal覆膜支架治疗颈部严重成角(角度>60°)的AAA在短期随访期间具有较高的技术成功率、低死亡率和低并发症发生率。