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采用Kilt技术对瘤颈解剖结构复杂的腹主动脉瘤进行血管内动脉瘤修复的临床结果:一项韩国多中心回顾性研究

Clinical Outcomes of Endovascular Aneurysm Repair with the Kilt Technique for Abdominal Aortic Aneurysms with Hostile Aneurysm Neck Anatomy: A Korean Multicenter Retrospective Study.

作者信息

Jeon Yong Sun, Cho Young Kwon, Song Myung Gyu, Seo Tae-Seok, Kim Jeong Ho, Song Soon-Young, Lee Sam Yeol

机构信息

Department of Radiology, Inha University Hospital, Inha University College of Medicine, Incheon, Korea.

Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150 Seongan-ro Gangdong-gu, Seoul, 134-701, Korea.

出版信息

Cardiovasc Intervent Radiol. 2018 Apr;41(4):554-563. doi: 10.1007/s00270-017-1867-y. Epub 2017 Dec 26.

Abstract

PURPOSE

We aimed to evaluate the clinical efficacy and short-term clinical outcomes of Kilt technique-based endovascular aneurysm repair (EVAR) with Seal stent-grafts for abdominal aortic aneurysms (AAAs) with hostile neck anatomy (angle > 60°).

MATERIALS AND METHODS

We retrospectively evaluated the pre-EVAR and follow-up computed tomography angiography findings of 24 patients (mean age 71 ± 11 years; age range 32-87 years; mean follow-up 50 ± 12 months) with hostile neck AAAs treated between 2010 and 2015. Serial change in aneurysmal neck angle was calculated using a standardized protocol. Relationships between clinical variables and outcomes were evaluated using univariate and multivariate Cox analyses and mixed-model regression. In addition, the Kaplan-Meier method was used to assess the cumulative rates of survival, endoleak, and reintervention.

RESULTS

The primary technical success rate (success within 24 h after EVAR) was 100% (24/24). The survival rate was 96 ± 8% at 1 month, 6 months, 1 year, and 3 years, and 87 ± 18% at 5 years. Endoleaks occurred in three patients. Four reinterventions were performed in three patients; no surgical revisions were required. Causes of post-EVAR mortality included intracerebral hemorrhage at 14 days and rhabdomyolysis at 32 months. The most remarkable change after Kilt-based EVAR was an acute decrease in the neck angle, which was observed between the pre-EVAR and first follow-up visits (at 1 month) (P = 0.001).

CONCLUSION

Kilt-based EVAR with Seal stent-grafts for AAAs with a severely angulated neck (angle > 60°) provided high technical success, low mortality, and low complication rates during short-term follow-up.

摘要

目的

我们旨在评估基于Kilt技术的带膜支架血管腔内修复术(EVAR)联合Seal覆膜支架治疗颈部解剖结构复杂(角度>60°)的腹主动脉瘤(AAA)的临床疗效和短期临床结局。

材料与方法

我们回顾性评估了2010年至2015年间接受治疗的24例颈部解剖结构复杂的AAA患者(平均年龄71±11岁;年龄范围32 - 87岁;平均随访50±12个月)的EVAR术前及随访期计算机断层扫描血管造影结果。使用标准化方案计算瘤颈角度的系列变化。采用单因素和多因素Cox分析以及混合模型回归评估临床变量与结局之间的关系。此外,使用Kaplan-Meier方法评估生存、内漏和再次干预的累积发生率。

结果

主要技术成功率(EVAR术后24小时内成功)为100%(24/24)。1个月、6个月、1年和3年时的生存率为96±8%,5年时为87±18%。3例患者发生内漏。3例患者进行了4次再次干预;无需手术翻修。EVAR术后死亡原因包括14天时的脑出血和32个月时的横纹肌溶解。基于Kilt技术的EVAR术后最显著的变化是瘤颈角度在EVAR术前与首次随访(1个月时)之间急剧减小(P = 0.001)。

结论

基于Kilt技术的EVAR联合Seal覆膜支架治疗颈部严重成角(角度>60°)的AAA在短期随访期间具有较高的技术成功率、低死亡率和低并发症发生率。

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