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唐氏综合征与小儿阻塞性睡眠呼吸暂停手术:一项全国队列研究。

Down syndrome and pediatric obstructive sleep apnea surgery: A national cohort.

作者信息

Ong Adrian A, Atwood Carlyn M, Nguyen Shaun A, Teufel Ronald J, Lal Chitra, LaRosa Angela C, White David R

机构信息

Department of Otolaryngology, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U.S.A.

出版信息

Laryngoscope. 2018 Aug;128(8):1963-1969. doi: 10.1002/lary.27063. Epub 2017 Dec 27.

DOI:10.1002/lary.27063
PMID:29280489
Abstract

OBJECTIVES/HYPOTHESIS: To analyze the trend of sleep surgeries in pediatric patients with Down syndrome (DS) and obstructive sleep apnea (OSA), and to compare this to nonsyndromic (NS) children with OSA.

STUDY DESIGN

Retrospective cohort database analysis.

METHODS

Analysis of the 1997 to 2012 editions of the Kid's Inpatient Database was conducted. Using International Classification of Diseases, Ninth Revision codes, all patients with OSA were identified, and subsequently, subgroups of NS children and children with DS were identified. Trends of the number and types of sleep surgeries were analyzed.

RESULTS

A total of 48,301 and 2,991 sleep surgeries were identified in the NS and DS groups, respectively, during the study period. Tonsillectomy with adenoidectomy was the most common procedure in both groups, but the proportion of tonsillectomy with adenoidectomy decreased over time (P < .01). The proportion of palatal surgery and tracheostomy also decreased significantly, whereas there was an increase in the proportion of lingual tonsillectomies, tongue-base reduction procedures, and supraglottoplasties performed in both groups over time. The relative rates of change in these procedures were higher in the DS population.

CONCLUSIONS

Tonsillectomy with adenoidectomy remains the most commonly performed procedure, although there was a significant increase in other sleep surgeries performed (lingual tonsillectomy, tongue-base reduction, and supraglottoplasty) between the two study periods, especially in children with DS.

LEVEL OF EVIDENCE

2c. Laryngoscope, 1963-1969, 2018.

摘要

目的/假设:分析唐氏综合征(DS)合并阻塞性睡眠呼吸暂停(OSA)患儿的睡眠手术趋势,并与非综合征性(NS)OSA患儿进行比较。

研究设计

回顾性队列数据库分析。

方法

对1997年至2012年版儿童住院数据库进行分析。使用国际疾病分类第九版编码,识别所有OSA患者,随后确定NS儿童和DS儿童亚组。分析睡眠手术的数量和类型趋势。

结果

在研究期间,NS组和DS组分别确定了48,301例和2,991例睡眠手术。扁桃体切除术加腺样体切除术是两组中最常见的手术,但扁桃体切除术加腺样体切除术的比例随时间下降(P < 0.01)。腭裂手术和气管切开术的比例也显著下降,而两组中舌扁桃体切除术、舌根缩小手术和声门上成形术的比例随时间增加。DS人群中这些手术的相对变化率更高。

结论

扁桃体切除术加腺样体切除术仍然是最常进行的手术,尽管在两个研究期间,其他睡眠手术(舌扁桃体切除术、舌根缩小术和声门上成形术)有显著增加,尤其是DS患儿。

证据级别

2c。《喉镜》,1963 - 1969年,2018年。

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