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穿孔球囊技术:一种简单易用的技术,可用于对抗冠状动脉无复流现象。

Perforated balloon technique: A simple and handy technique to combat no-reflow phenomenon in coronary system.

机构信息

Apex Heart Institute, Ahmedabad, India.

Department of Cardiology, Sheth V.S. General Hospital and Smt. N.H.L. Municipal Medical College, Ahmedabad, 380 006, India.

出版信息

Catheter Cardiovasc Interv. 2018 Nov 1;92(5):890-894. doi: 10.1002/ccd.27477. Epub 2017 Dec 27.

Abstract

OBJECTIVE

Examining the efficacy and outcomes of intracoronary (IC) instillation of adenosine using a novel perforated balloon technique (PBT) to combat no-reflow phenomenon during percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS).

BACKGROUND

Occurrence of no-reflow during PCI is a serious adverse prognostic event and inability to re-establish better flow is associated with poor outcomes. Several pharmacological and non-pharmacological interventions have been used to treat this situation. This series describes the use of PBT for IC adenosine administration and its effects on outcomes during real world interventional practice.

METHODS

Subjects comprised of 24 patients with ACS (out of a total of 1,634 patients undergoing PCI between January 2016 and June 2017) in whom we used PBT for IC administration of adenosine to treat coronary no-reflow.

RESULTS

PBT for IC adenosine instillation was used in 24 (1.5%) of 1,634 patients undergoing PCI. TIMI grade III flow was established in 21 patients (87.5%). In two patients (8.3%) TIMI grade II flow was established and in one patient (4.2%) we were unsuccessful.

CONCLUSION

We demonstrate the safety and efficacy of a novel strategy for adenosine instillation in the distal coronary bed, the PBT. This technique enables rapid and cost-effective treatment of no-reflow phenomenon during PCI for ACS.

摘要

目的

研究使用新型穿孔球囊技术(PBT)经冠状动脉内(IC)注射腺苷以对抗急性冠脉综合征(ACS)经皮冠状动脉介入治疗(PCI)中无复流现象的疗效和结果。

背景

PCI 过程中发生无复流是一种严重的不良预后事件,无法恢复更好的血流与不良结局相关。已经使用了几种药物和非药物干预措施来治疗这种情况。本系列描述了使用 PBT 进行 IC 腺苷给药及其对真实世界介入治疗中结果的影响。

方法

研究对象包括 24 例 ACS 患者(在 2016 年 1 月至 2017 年 6 月期间进行的 1634 例 PCI 患者中),我们使用 PBT 进行 IC 腺苷给药以治疗冠状动脉无复流。

结果

在 1634 例行 PCI 的患者中,有 24 例(1.5%)使用 PBT 进行 IC 腺苷灌注。21 例患者(87.5%)建立了 TIMI 血流 III 级。在 2 例患者(8.3%)中建立了 TIMI 血流 II 级,在 1 例患者(4.2%)中我们未能成功。

结论

我们证明了一种新型策略用于 ACS 经皮冠状动脉介入治疗中远端冠状动脉床腺苷灌注的安全性和有效性,即 PBT。该技术可快速、经济有效地治疗 PCI 中的无复流现象。

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