El-Khoury Joseph S, Jabbour Samer F, Awaida Cyril J, Rayess Youssef A, Kechichian Elio G, Nasr Marwan W
Beirut, Lebanon.
From the Departments of Plastic and Reconstructive Surgery and Dermatology, Faculty of Medicine, Saint-Joseph University Hotel Dieu de France Hospital.
Plast Reconstr Surg. 2018 Jan;141(1):75-78. doi: 10.1097/PRS.0000000000003919.
Previous reports have objectively demonstrated the efficacy of botulinum toxin for brow elevation. No clinical trial has compared the variation of the eyebrow shape and height when the lateral eyebrow depressors are injected alone or in combination with the medial eyebrow depressors.
A prospective, randomized, controlled study was designed to evaluate and compare the effect of two different botulinum toxin injection techniques on brow shape and position. Patients were divided into two groups. AbobotulinumtoxinA was injected in the lateral eyebrow depressors alone (group 1) or in both the lateral and medial eyebrow depressors (group 2). Objective eyebrow measurements were performed using standardized preinjection and postinjection photographs. Patient satisfaction was also evaluated.
Fifteen patients (30 eyebrows) were included in each group. The brow elevated by 0.6 to 2.1 mm at all positions in group 1. In group 2, the brow elevated from the medial limbus to the lateral edge of the brow (1 to 1.7 mm), with no changes at the level of the medial brow and canthus. When comparing the two injection techniques, the authors found a statistically significant difference in the change of eyebrow height at the level of the medial brow, medial canthus, and lateral brow edge. Ninety-seven percent of patients were satisfied with their results.
Different eyebrow injection techniques yield different elevation patterns.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II.
既往报道已客观证实肉毒杆菌毒素对抬高眉部有效。尚无临床试验比较单独注射外侧眉下压肌或联合注射内侧眉下压肌时眉形和眉高的变化。
设计一项前瞻性、随机对照研究，以评估和比较两种不同肉毒杆菌毒素注射技术对眉形和位置的影响。患者分为两组。仅在外侧眉下压肌注射阿泊肉毒杆菌毒素A（第1组）或同时在外侧和内侧眉下压肌注射（第2组）。使用注射前和注射后的标准化照片对眉部进行客观测量。还评估了患者满意度。
每组纳入15例患者（30侧眉）。第1组所有位置的眉部抬高0.6至2.1毫米。在第2组中，眉部从内眦抬高至眉外侧边缘（1至1.7毫米），眉内侧和内眦水平无变化。比较两种注射技术时，作者发现眉内侧、内眦和眉外侧边缘水平的眉高变化有统计学显著差异。97%的患者对结果满意。
不同的眉部注射技术产生不同的抬高模式。
临床问题/证据水平：治疗性，II级。
