用于防治油棕灵芝病的（己唑醇-锌/铝层状双氢氧化物纳米复合材料）杀菌剂纳米递送系统的合成

Synthesis of (Hexaconazole-Zinc/Aluminum-Layered Double Hydroxide Nanocomposite) Fungicide Nanodelivery System for Controlling Ganoderma Disease in Oil Palm.

作者信息

Mustafa Isshadiba F, Hussein Mohd Zobir, Saifullah Bullo, Idris Abu Seman, Hilmi Nur Hailini Z, Fakurazi Sharida

机构信息

Materials Synthesis and Characterization Laboratory, Institute of Advanced Technology, Universiti Putra Malaysia , 43400 UPM Serdang, Selangor, Malaysia.

Malaysian Palm Oil Board (MPOB) , No.6, Persiaran Institusi, Bandar Baru Bangi, 43000 Kajang, Selangor, Malaysia.

出版信息

J Agric Food Chem. 2018 Jan 31;66(4):806-813. doi: 10.1021/acs.jafc.7b04222. Epub 2018 Jan 16.

DOI:10.1021/acs.jafc.7b04222

PMID:29281878

Abstract

A fungicide, hexaconazole was successfully intercalated into the intergalleries of zinc/aluminum-layered double hydroxide (ZALDH) using the ion-exchange method. Due to the intercalation of hexaconazole, the basal spacing of the ZALDH was increased from 8.7 Å in ZALDH to 29.4 Å in hexaconazole-intercalated ZALDH (HZALDH). The intercalation of hexaconazole into the interlayer of the nanocomposite was confirmed using the Fourier-transform infrared (FTIR) study. This supramolecular chemistry intercalation process enhanced the thermal stability of the hexaconazole moiety. The fungicide loading was estimated to be 51.8%. The nanodelivery system also shows better inhibition toward the Ganoderma boninense growth than the counterpart, free hexaconazole. The results from this work have a great potential to be further explored for combating basal stem rot (BSR) disease in oil palm plantation.

摘要

一种杀菌剂己唑醇通过离子交换法成功插层进入锌/铝层状双氢氧化物（ZALDH）的层间。由于己唑醇的插层，ZALDH的层间距从ZALDH中的8.7 Å增加到己唑醇插层ZALDH（HZALDH）中的29.4 Å。利用傅里叶变换红外光谱（FTIR）研究证实了己唑醇插入纳米复合材料的层间。这种超分子化学插层过程提高了己唑醇部分的热稳定性。杀菌剂负载量估计为51.8%。该纳米递送系统对灵芝的生长抑制效果也优于游离己唑醇。这项工作的结果在防治油棕种植园的基干腐病方面具有很大的进一步探索潜力。