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骨盆骨折患者血管造影中活动性动脉出血的预测因素。

Predictors of active arterial hemorrhage on angiography in pelvic fracture patients.

机构信息

Division of Emergency and Critical Care Radiology, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu-Hsing Street, Gueishan, Taoyuan, 333, Taiwan.

出版信息

Jpn J Radiol. 2018 Mar;36(3):223-230. doi: 10.1007/s11604-017-0716-x. Epub 2017 Dec 27.

Abstract

PURPOSE

To determine predictors of active angiographic hemorrhage in pelvic fracture patients.

MATERIALS AND METHODS

This retrospective study included 66 trauma patients who had major hemorrhages due to pelvic fractures, and who underwent pelvic angiography between January 2012 and December 2014. The study population comprised 31 males and 35 females (mean age 44.2 ± 20.7 years). The main outcome was active hemorrhage on pelvic angiography. Clinical and imaging variables including demographics, hemodynamic parameters, injury severity, types of pelvic fracture, laboratory data, blood transfusions and CT findings were analyzed. Multivariate logistic regression was used to identify predictors of active angiographic hemorrhage.

RESULTS

Of the 66 study patients included, 41 patients had active angiographic hemorrhage. These patients had more blood transfusions, higher activated partial thromboplastin times and higher rates of contrast extravasation on CT (p < 0.05). Three independent predictors of active angiographic hemorrhage were identified, including contrast extravasation on CT (OR: 74.6, p < 0.001), more than 8 units of RBC transfusions (OR: 12.5, p = 0.018) and ISS ≥ 16 (OR: 11.1, p = 0.029).

CONCLUSION

Contrast extravasation on CT, high volume RBC transfusions and ISS ≥ 16 can help us to select pelvic fracture patients for angiography more precisely.

摘要

目的

确定骨盆骨折患者活动性血管造影出血的预测因素。

材料与方法

本回顾性研究纳入了 2012 年 1 月至 2014 年 12 月期间因骨盆骨折而发生大出血并接受骨盆血管造影的 66 例创伤患者。研究人群包括 31 名男性和 35 名女性(平均年龄 44.2±20.7 岁)。主要结局是骨盆血管造影上的活动性出血。分析了包括人口统计学、血流动力学参数、损伤严重程度、骨盆骨折类型、实验室数据、输血和 CT 发现在内的临床和影像学变量。采用多变量逻辑回归分析确定活动性血管造影出血的预测因素。

结果

在 66 例研究患者中,有 41 例患者存在活动性血管造影出血。这些患者的输血量更多,活化部分凝血活酶时间更高,CT 上对比剂外渗的发生率更高(p<0.05)。确定了 3 个活动性血管造影出血的独立预测因素,包括 CT 上的对比剂外渗(OR:74.6,p<0.001)、超过 8 单位的红细胞输血(OR:12.5,p=0.018)和 ISS≥16(OR:11.1,p=0.029)。

结论

CT 上的对比剂外渗、大量红细胞输血和 ISS≥16 可帮助我们更精确地选择需要进行血管造影的骨盆骨折患者。

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