一只自由生活的狨猴（绢毛猴属）患肝细胞癌并伴有胆管吸虫病。

Hepatocellular carcinoma in a free-living marmoset (Callithrix sp.) with concomitant biliary trematodiasis.

作者信息

Díaz-Delgado J, Sanches T C, Dos Santos-Cirqueira C, Coimbra A A C, Guerra J M, Joppert A, Di Loretto C, Rizardi M B, Sansone M, Nagamori F O, Gonçalves P S, Ressio R, Iglezias S, Fernandes N C C A, Kanamura C, Groch K R, Catão-Dias J L

机构信息

Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, SP, Brasil.

Centro de Patologia, Instituto Adolfo Lutz (IAL), São Paulo, SP, Brazil.

出版信息

J Med Primatol. 2018 Apr;47(2):128-131. doi: 10.1111/jmp.12329. Epub 2017 Dec 28.

DOI:10.1111/jmp.12329

PMID:29283447

Abstract

Hepatocellular carcinoma (HCC) is rare in New World primates. We report the gross, microscopical, and immunocytochemical features of a spontaneous HCC in a free-living marmoset (Callithrix sp.). Hepatitis B and C virus and aflatoxin immunohistochemistry were negative; however, concomitant intra- and extrahepatic biliary trematodiasis could have played a role.

摘要

肝细胞癌（HCC）在新大陆灵长类动物中较为罕见。我们报告了一只自由生活的狨猴（Callithrix sp.）自发性肝细胞癌的大体、显微镜和免疫细胞化学特征。乙肝和丙肝病毒以及黄曲霉毒素免疫组化结果均为阴性；然而，同时存在的肝内和肝外胆管吸虫病可能起到了一定作用。