添加 N-杂环卡宾催化剂诱导芳基酯远程 C-Si 键活化和苄位碳官能化。
Addition of N-Heterocyclic Carbene Catalyst to Aryl Esters Induces Remote C-Si Bond Activation and Benzylic Carbon Functionalization.
机构信息
Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University , Huaxi District, Guiyang 550025, People's Republic of China.
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , 21 Nanyang Link, Singapore 637371.
出版信息
Org Lett. 2018 Jan 19;20(2):333-336. doi: 10.1021/acs.orglett.7b03544. Epub 2017 Dec 29.
Through the incorporation of a silicon atom to an aryl carboxylic ester substrate, the resulting C-Si bond can be activated via the addition of a carbene catalyst on a remote site. This strategy allows for efficient functionalization of the benzylic sp-carbons of aryl carboxylic esters.
通过将硅原子引入芳基羧酸酯底物中，可以通过在远程位置添加卡宾催化剂来激活生成的 C-Si 键。该策略允许对芳基羧酸酯的苄基 sp-碳进行有效的功能化。
Zotero 插件