School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Jiangsu Marine Resources Development Research Institute, Lianyungang 222005, China.
Food Chem. 2018 Apr 15;245:346-352. doi: 10.1016/j.foodchem.2017.10.110. Epub 2017 Oct 25.
Polyethylene glycol (PEG) is widely used in the polymer-salt systems. However, the low polarity of the PEG-rich phase limits the application of aqueous biphasic systems (ABS). To overcome this disadvantage, a small quantity of ionic liquid (IL) was used as an adjuvant in ABS to enlarge the polarity range. Therefore, an innovative study involving addition of 4wt% imidazolium-based ILs to the PEG 600/NaHPO ABS, aiming at controlling the phase behavior and extraction ability, was carried out. The phase diagrams, the tie-lines and the partitioning behavior of l-phenylalanine and ILs were studied in these systems. The results reveal that l-phenylalanine preferentially partitions for the PEG-rich phase. The addition of 4wt% IL to ABS controls the partitioning behavior of l-phenylalanine, which depends on the type of IL employed. Moreover, it is verified that increasing temperature lead to a decrease in the partition coefficient of l-phenylalanine.
聚乙二醇（PEG）在聚合物-盐体系中被广泛应用。然而，PEG 丰富相的低极性限制了双水相体系（ABS）的应用。为了克服这一缺点，在 ABS 中加入少量离子液体（IL）作为助剂，以扩大极性范围。因此，进行了一项创新性研究，即在 PEG 600/NaHPO4 ABS 中加入 4wt%的基于咪唑的离子液体，旨在控制相行为和萃取能力。研究了这些体系的相图、连接线和 L-苯丙氨酸和离子液体的分配行为。结果表明，L-苯丙氨酸优先分配到 PEG 丰富相。向 ABS 中加入 4wt%的 IL 控制了 L-苯丙氨酸的分配行为，这取决于所使用的 IL 的类型。此外，验证了升高温度会导致 L-苯丙氨酸的分配系数降低。
