Zhang Lili, Liu Yujiang, Tan Xiaoqu, Liu Xi, Zhang Hong, Qian Linxue
Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
J Ultrasound Med. 2018 Jul;37(7):1713-1716. doi: 10.1002/jum.14521. Epub 2017 Dec 30.
To compare the adequacy of 23-, 25-, and 27-gauge needles in the fine-needle aspiration biopsy of thyroid nodules to develop guidelines for the collection of better specimens for cytologic diagnosis.
This randomized prospective study included 156 consecutively enrolled patients with 156 nodules. Each nodule was aspirated with a needle of each size. The obtained specimens were analyzed independently by 2 cytopathologists, and adequacy rates were calculated.
In our investigation, there were no statistically significant differences among the adequacy rates achieved with 23-, 25-, and 27-gauge needles (88.5%, 90.4%, and 89.7%, respectively; P > .05). The adequacy rates achieved with all 3 needle sizes in hyperechoic nodules were higher than those in hypoechoic samples (P < .05). Finally, no differences in adequacy for the different needle sizes were observed according to nodule size (P > .05).
We conclude that fine-needle aspiration biopsy with a 27-gauge needle can aspirate an adequate specimen for cytopathologic diagnosis of thyroid nodules. The likelihood that inadequate materials will be obtained from hypoechoic nodules is higher than that for hyperechoic nodules.
比较23号、25号和27号针在甲状腺结节细针穿刺活检中的取材 adequacy，以制定获取更好的细胞学诊断标本的 guidelines。
这项随机前瞻性研究纳入了156例连续入组的患者，共156个结节。每个结节均用每种型号的针进行穿刺。所获得的标本由2名细胞病理学家独立分析，并计算取材 adequacy 率。
在我们的研究中，23号、25号和27号针的取材 adequacy 率之间无统计学显著差异（分别为88.5%、90.4%和89.7%；P＞0.05）。高回声结节中所有3种针型号的取材 adequacy 率均高于低回声样本（P＜0.05）。最后，根据结节大小，未观察到不同针型号在取材 adequacy 方面的差异（P＞0.05）。
我们得出结论，使用27号针进行甲状腺结节细针穿刺活检能够获取足够的标本用于细胞病理学诊断。从低回声结节获取不足材料的可能性高于高回声结节。
