• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[以巨细胞动脉炎为表现的肺出血肾炎综合征]

[A giant cell arteritis revealing a Goodpasture's syndrome].

作者信息

Alix Pascaline M, Belloi Amélie, Berthoux Émilie, Dijoud Frédérique, Villar Emmanuel, Pariset Caroline

机构信息

Service de néphrologie, hôpital Édouard-Herriot, hospices civils de Lyon, 3, place d'Arsonval, 69347 Lyon cedex, France.

Service de néphrologie, centre hospitalier Saint-Joseph-Saint-Luc, 20, quai Claude-Bernard, 69007 Lyon, France.

出版信息

Nephrol Ther. 2018 Apr;14(2):105-108. doi: 10.1016/j.nephro.2017.09.004. Epub 2017 Dec 28.

DOI:10.1016/j.nephro.2017.09.004
PMID:29290619
Abstract

Goodpasture's syndrome is a triad of anti-glomerular basement membrane (anti-GBM) circulating antibodies, glomerulonephritis and pulmonary hemorrhage. We reported a 65-year-old woman with headaches, asthenia and weight loss. Giant cell arteritis was confirmed by temporal artery biopsy. The patient had associated renal condition with moderate acute renal failure, proteinuria and haematuria. Renal biopsy showed extracapillary glomerulonephritis and linear staining of immunoglobulins G along glomerular basement membrane. There was no clinical pulmonary involvement. Anti-MBG antibody was positive and allowed Goodpasture's syndrome diagnosis. The patient was treated with corticoids and cyclophosphamide. Patient's condition and renal function improved quickly and anti-MBG antibodies became negative. Goodpasture's syndrome may be characterized by isolated renal expression without pulmonary involvement. We described for the first time association of Goodpasture's syndrome with giant cell arteritis.

摘要

古德帕斯彻综合征是由抗肾小球基底膜(抗GBM)循环抗体、肾小球肾炎和肺出血组成的三联征。我们报告了一名65岁女性,有头痛、乏力和体重减轻症状。颞动脉活检确诊为巨细胞动脉炎。该患者伴有肾脏疾病,有中度急性肾衰竭、蛋白尿和血尿。肾活检显示毛细血管外肾小球肾炎以及免疫球蛋白G沿肾小球基底膜呈线性染色。无临床肺部受累表现。抗MBG抗体阳性,确诊为古德帕斯彻综合征。患者接受了皮质类固醇和环磷酰胺治疗。患者病情和肾功能迅速改善,抗MBG抗体转阴。古德帕斯彻综合征可能以无肺部受累的孤立性肾脏表现为特征。我们首次描述了古德帕斯彻综合征与巨细胞动脉炎的关联。

相似文献

1
[A giant cell arteritis revealing a Goodpasture's syndrome].[以巨细胞动脉炎为表现的肺出血肾炎综合征]
Nephrol Ther. 2018 Apr;14(2):105-108. doi: 10.1016/j.nephro.2017.09.004. Epub 2017 Dec 28.
2
Goodpasture's syndrome with absence of circulating anti-glomerular basement membrane antibodies: a case report.循环抗肾小球基底膜抗体阴性的肺出血肾炎综合征:一例报告
J Med Case Rep. 2016 Jul 27;10:205. doi: 10.1186/s13256-016-0984-6.
3
[Review on anti-glomerular basement membrane disease or Goodpasture's syndrome].[抗肾小球基底膜病或古德帕斯彻综合征综述]
Rev Med Interne. 2020 Jan;41(1):14-20. doi: 10.1016/j.revmed.2019.10.338. Epub 2019 Nov 24.
4
Goodpasture's syndrome with concomitant immune complex mixed membranous and proliferative glomerulonephritis.伴有免疫复合物混合性膜性和增殖性肾小球肾炎的肺出血肾炎综合征。
Clin Nephrol. 2014 Mar;81(3):216-23. doi: 10.5414/CN107454.
5
Goodpasture's syndrome in a child: natural history and effect of treatment.儿童肺出血肾炎综合征:自然病史及治疗效果
Acta Paediatr Scand. 1981;70(3):435-9. doi: 10.1111/j.1651-2227.1981.tb16581.x.
6
Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques.经标准技术检测,无循环抗肾小球基底膜抗体情况下的肺出血肾炎综合征。
Am J Kidney Dis. 2002 Jun;39(6):1162-7. doi: 10.1053/ajkd.2002.33385.
7
A case report of efficiency of double filtration plasmapheresis in treatment of Goodpasture's syndrome.双重滤过血浆置换治疗肺出血肾炎综合征疗效的病例报告
Ther Apher Dial. 2009 Aug;13(4):373-7. doi: 10.1111/j.1744-9987.2009.00687.x. Epub 2009 Apr 21.
8
[Goodpasture's disease or syndrome? Apropos of a case].[肺出血肾炎综合征还是综合征?关于一例病例]
Recenti Prog Med. 1997 Jan;88(1):26-31.
9
Goodpasture's disease: a report of ten cases and a review of the literature.Goodpasture 综合征:10 例报告及文献复习。
Autoimmun Rev. 2013 Sep;12(11):1101-8. doi: 10.1016/j.autrev.2013.06.014. Epub 2013 Jun 24.
10
Atypical Goodpasture's disease: a clinical case report and literature review.非典型Goodpasture病:一例临床病例报告及文献综述
Ter Arkh. 2018 Jun 20;90(6):130-136. doi: 10.26442/terarkh2018906130-136.