Treating hot flushes with a neurokinin 3 receptor antagonist.
作者信息
Prague Julia K, Dhillo Waljit S
机构信息
Waljit S. Dhillo: Department of Investigative Medicine, Imperial College London, London, UK.
出版信息
Oncotarget. 2017 Nov 11;8(63):106153-106154. doi: 10.18632/oncotarget.22383. eCollection 2017 Dec 5.
Abstract
摘要
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Oncotarget. 2017 Nov 11;8(63):106153-106154. doi: 10.18632/oncotarget.22383. eCollection 2017 Dec 5.
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Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial.神经激肽 3 受体拮抗剂作为治疗更年期潮热的一种新方法：一项 2 期、随机、双盲、安慰剂对照试验。
Lancet. 2017 May 6;389(10081):1809-1820. doi: 10.1016/S0140-6736(17)30823-1. Epub 2017 Apr 3.
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MsFLASH participants' priorities for alleviating menopausal symptoms.MsFLASH研究参与者缓解更年期症状的优先事项。
Climacteric. 2015;18(6):859-66. doi: 10.3109/13697137.2015.1083003. Epub 2015 Oct 30.
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Neurokinin 3 Receptor-Expressing Neurons in the Median Preoptic Nucleus Modulate Heat-Dissipation Effectors in the Female Rat.视前正中核中表达神经激肽3受体的神经元调节雌性大鼠的散热效应器。
Endocrinology. 2015 Jul;156(7):2552-62. doi: 10.1210/en.2014-1974. Epub 2015 Mar 31.
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Duration of menopausal vasomotor symptoms over the menopause transition.绝经过渡期间绝经血管舒缩症状的持续时间。
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Neurokinin B administration induces hot flushes in women.给予神经激肽B可诱发女性潮热。
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Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: a novel hypothesis on the mechanism of hot flushes.下丘脑 KNDy（促 kisspeptin、神经激肽 B 和强啡肽）神经元对体温和 LH 分泌的调制：热潮红发生机制的新假说。
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