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Host histone acetylation unlocks HDAC inhibitor potential.

作者信息

Terranova-Barberio Manuela, Thomas Scott, Munster Pamela N

机构信息

Pamela N. Munster: Department of Medicine, Division of Hematology and Oncology, Helen Diller Family Cancer Center, University of California, San Francisco, CA, USA.

出版信息

Oncotarget. 2017 Nov 13;8(63):106161-106162. doi: 10.18632/oncotarget.22422. eCollection 2017 Dec 5.

DOI:10.18632/oncotarget.22422
PMID:29290932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5739717/
Abstract
摘要

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Oncotarget. 2017 Jun 13;8(24):39241-39253. doi: 10.18632/oncotarget.16843.
2
Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies.抑制组蛋白去乙酰化酶作为逆转对血管生成抑制剂耐药性的一种手段:阿贝西诺特联合帕唑帕尼治疗晚期实体瘤的I期研究。
J Clin Oncol. 2017 Apr 10;35(11):1231-1239. doi: 10.1200/JCO.2016.70.5350. Epub 2017 Feb 21.
3
Gene expression profiling of circulating tumor cells and peripheral blood mononuclear cells from breast cancer patients.乳腺癌患者循环肿瘤细胞和外周血单个核细胞的基因表达谱分析。
Oncoimmunology. 2015 Dec 10;5(4):e1102827. doi: 10.1080/2162402X.2015.1102827. eCollection 2016 Apr.
4
Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitor.随机、二期、双盲、安慰剂对照研究依西美坦联合或不联合恩替诺特治疗接受非甾体芳香化酶抑制剂治疗后局部复发或转移性雌激素受体阳性乳腺癌进展的绝经后妇女。
J Clin Oncol. 2013 Jun 10;31(17):2128-35. doi: 10.1200/JCO.2012.43.7251. Epub 2013 May 6.
5
Methods for the analysis of histone H3 and H4 acetylation in blood.用于分析血液中组蛋白 H3 和 H4 乙酰化的方法。
Epigenetics. 2012 Aug;7(8):875-82. doi: 10.4161/epi.20983. Epub 2012 Jul 9.
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A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer.一项评估组蛋白去乙酰化酶抑制剂伏立诺他联合他莫昔芬治疗激素治疗抵抗性乳腺癌患者的 II 期临床研究。
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