Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Kidney Int. 2018 Jan;93(1):18-20. doi: 10.1016/j.kint.2017.08.001.
The 2012 Systemic Lupus International Collaborating Clinics criteria propose the classification of systemic lupus erythematosus (SLE) by biopsy-confirmed lupus nephritis plus circulating antinuclear antibody or anti-double-stranded DNA antibody. Application of this stand-alone renal criterion to a cohort of patients with "full-house" glomerular deposits resulted in mistaken classification of SLE in some cases with antinuclear antibody. More precise biopsy criteria using a constellation of characteristic features are needed to optimize the kidney biopsy standard for lupus nephritis.
2012 年系统性红斑狼疮国际协作组提出的分类标准，将系统性红斑狼疮（SLE）分为经肾活检证实的狼疮肾炎伴循环抗核抗体或抗双链 DNA 抗体阳性。将该单纯肾脏标准应用于“满堂红”肾小球沉积的患者队列中，导致一些抗核抗体阳性的患者被错误分类为 SLE。需要更精确的使用一系列特征性表现的肾活检标准来优化狼疮肾炎的肾活检标准。
