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[磁共振成像评估膝关节软骨的研究进展]

[Progress on magnetic resonance imaging for evaluating the articular cartilage of the knee joint].

作者信息

Yang Guang-Yue, Guo Hai-Ling, Li Tao, Zhao Yong-Fang

机构信息

Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese Medicine, Shanghai 201203, China.

Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Institute of Traumatology & Orthopedics, Shanghai Academy of Traditional Chinese Medicine, Shanghai 201203, China;

出版信息

Zhongguo Gu Shang. 2016 Nov 25;29(11):1061-1067. doi: 10.3969/j.issn.1003-0034.2016.11.018.

DOI:10.3969/j.issn.1003-0034.2016.11.018
PMID:29292647
Abstract

The reasonable selection of magnetic resonance imaging(MRI) scan sequence and parameters is very important for the objective evaluation of the results of clinical study and high quality imaging. The semi quantitative scoring system of total knee joint including Whole Organ Magnetic Resonance Imaging Score, Boston Leeds Osteoarthritis Knee Score, MRI Osteoarthritis Knee Score, Cartilage Repair Osteoarthritis Knee Score and so on. They can fully evaluate the imaging changes of various organs during the development of knee osteoarthritis. With the continuous development of MRI technology, the morphological and physiological changes of articular cartilage can be quantitatively assessed. T2 mapping, Diffusion Weighted Imaging, and delayed Gadolinium-Enhanced MRI of Cartilage can be quantitatively monitoring changes in cartilage matrix components. These quantitative and semi quantitative evaluation techniques are helpful to detect OA in its early stage, guide clinical early intervention, and also provide the possibility for the accurate evaluation of the therapeutic effect.

摘要

合理选择磁共振成像(MRI)扫描序列和参数对于客观评估临床研究结果及获得高质量影像非常重要。全膝关节的半定量评分系统包括全器官磁共振成像评分、波士顿利兹骨关节炎膝关节评分、MRI骨关节炎膝关节评分、软骨修复骨关节炎膝关节评分等。它们能够全面评估膝关节骨关节炎发展过程中各个器官的影像变化。随着MRI技术的不断发展,关节软骨的形态和生理变化能够得到定量评估。T2映射、扩散加权成像以及延迟钆增强软骨磁共振成像能够定量监测软骨基质成分的变化。这些定量和半定量评估技术有助于早期检测骨关节炎,指导临床早期干预,也为准确评估治疗效果提供了可能。

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