State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University , Nanjing 210096, China.
Anal Chem. 2018 Feb 6;90(3):1482-1486. doi: 10.1021/acs.analchem.7b03790. Epub 2018 Jan 5.
We report a quantitative analytical method using the naked eye. The method is based on the coffee-ring effect on paper, which converts a colored solution to stains on the paper. It is found that the width of the colored stains is correlated to the concentration of analyte so that quantitative analysis can be accomplished using a ruler. The influence of the shape and lamination of the paper reservoir to the test results is studied to find the optimal one for unambiguous analysis. It is also found that the sample color does not cause interference to the test. The applicability of the method to quantitative chemical analysis is demonstrated by detection of glucose and lactate.
我们报告了一种使用肉眼的定量分析方法。该方法基于纸张上的咖啡环效应，将有色溶液转化为纸张上的污渍。结果发现，有色污渍的宽度与分析物的浓度相关，因此可以使用尺子进行定量分析。研究了纸张储液器的形状和层压对测试结果的影响，以找到用于明确分析的最佳形状和层压。还发现样品颜色不会对测试造成干扰。通过检测葡萄糖和乳酸验证了该方法在定量化学分析中的适用性。
