From the Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Clin Nucl Med. 2018 Mar;43(3):217-219. doi: 10.1097/RLU.0000000000001964.
Concurrent extramedullary infiltration in multiple organs is uncommon in adults with acute lymphoblastic leukemia. A 21-year-old woman who presented fatigue had a new diagnosis of acute lymphoblastic leukemia underwent FDG PET/CT. The images demonstrated extramedullary infiltration in multiple organs, including the liver, pancreas, kidney and the bone. However, no clinical signs or laboratory tests were suggestive of the involvement of these organs. After four cycles of chemotherapy, the patient's symptoms were relieved and all previously visualized abnormal activity disappeared on the follow-up FDG PET/CT.
成人急性淋巴细胞白血病并发多器官髓外浸润并不常见。一位 21 岁女性因疲劳就诊,新诊断为急性淋巴细胞白血病,行 FDG PET/CT 检查。图像显示多器官髓外浸润,包括肝脏、胰腺、肾脏和骨骼。然而,没有临床症状或实验室检查提示这些器官受累。经过四个周期的化疗,患者症状缓解,随访 FDG PET/CT 上所有先前显示的异常活性均消失。