Department of Chemistry, University of South Florida , 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States.
Center for Drug Discovery and Innovation, University of South Florida , 3720 Spectrum Boulevard, Suite 303, Tampa, Florida 33612, United States.
Org Lett. 2018 Jan 19;20(2):381-384. doi: 10.1021/acs.orglett.7b03668. Epub 2018 Jan 2.
A practical synthetic approach to Δ-tetrahydrocannabinol (1) and cannabidiol (2) that provides scalable access to these natural products and should enable the generation of novel synthetic analogues is reported.
报道了一种实用的 Δ-四氢大麻酚(1)和大麻二酚(2)的合成方法,该方法为这些天然产物提供了可扩展的途径,并且应该能够生成新型的合成类似物。