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[急性硫化氢中毒患者肺损伤CT评分与氧合指数的相关性]

[The correlation between CT score of lung injury and oxygenation index in patients with acute hydrogen sulphide poisoning].

作者信息

Yang Z H, Xu Y M, Jiang X Y, Lin J J, Wang D S, Chen Y L, Zhao H L

机构信息

CT department of Wenling First People's Hospital, Taizhou 317500, China.

出版信息

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2017 Sep 20;35(9):691-694. doi: 10.3760/cma.j.issn.1001-9391.2017.09.012.

DOI:10.3760/cma.j.issn.1001-9391.2017.09.012
PMID:29294524
Abstract

To explore correlation between chest CT score and oxygenation index in patients with acute hydrogen sulphide poisoning, whether CT score can be applied to assess acute lung injury after acute hydrogen sulfide poisoning and provide basis and reference. The clinic and a series of CT datas of 32 acute hydrogen sulphide poisoning cases were retrospectively analysed and compared, According to GBZ31-2002 (the diagnostic standard of occupational H(2)S acute poisoning) , these patients were divided into 2 grouds including moderate groud and severe groud; The CT score were improved, referenceing the scoring criteria of the chest X-ray; The difference of the CT score and the oxygenation index were analyzed between moderate and severe group in the acute phase and the disperse phase; The correlation between CT score and oxygenation index were analyzed. The CT score in moderate poisoning group were lower than severe group (2.26±1.37 vs 10.44±2.55, 1.34±0.65 vs 4.55±2.45, all P<0.05) in the acute phase and the dissipation phase.The oxygen index of the 19 cases in the acute phase were 307.55±28.29, and the oxygen index of the 8 cases in the dissipation phase was 435.75±37.00; The oxygen index of the 9 cases in the acute phase and the dissipation phase were respectively 193.17±36.41, 347.67±44.49. The oxygen partial pressure and oxygenation index in severe group were significantly lower than those in moderate group (all P<0.01) in the acute phase and the dissipation phase. Pearman correlation analysis showed that the CT score were negatively correlated to the oxygen index in the acute phase and the dissipation phase, respectively (r=-0.97、-0.75, all P<0.01) . The CT score of lung injury and oxygenation index is negatively correlated. The CT score can be used to evaluate the degree of lung injury, and can be used in the evaluation of acute lung injury after acute hydrogen sulfide poisoning.

摘要

为探讨急性硫化氢中毒患者胸部CT评分与氧合指数之间的相关性,以及CT评分能否用于评估急性硫化氢中毒后急性肺损伤情况,为临床提供依据和参考。回顾性分析32例急性硫化氢中毒患者的临床资料及一系列胸部CT数据,并进行对比。根据GBZ31 - 2002(职业性急性硫化氢中毒诊断标准),将患者分为中度组和重度组;参照胸部X线评分标准对CT评分进行改良;分析急性期和消散期中度组与重度组CT评分及氧合指数的差异;分析CT评分与氧合指数的相关性。结果显示,急性期和消散期中度中毒组CT评分均低于重度组(分别为2.26±1.37 vs 10.44±2.55,1.34±0.65 vs 4.55±2.45,均P<0.05)。急性期19例患者氧合指数为307.55±28.29,消散期8例患者氧合指数为435.75±37.00;急性期和消散期9例患者氧合指数分别为193.17±36.41、347.67±44.49。急性期和消散期重度组氧分压及氧合指数均显著低于中度组(均P<0.01)。Pearman相关性分析显示,急性期和消散期CT评分分别与氧合指数呈负相关(r=-0.97、-0.75,均P<0.01)。肺损伤CT评分与氧合指数呈负相关。CT评分可用于评估肺损伤程度,可用于急性硫化氢中毒后急性肺损伤的评估。

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