放射性相关脑膜瘤：重复放疗的情况
Radiation Associated Meningiomas:The Case for Repeat Radiotherapy.
作者信息
Smee Robert I
机构信息
Department of Radiation Oncology, The Prince of Wales Cancer Centre, High St, Randwick, New South Wales, Australia.
出版信息
J Radiosurg SBRT. 2011;1(2):141-145.
PURPOSE
To evaluate the circumstances relating to Radiation Associated Meningiomas (RAM) and whether repeat radiotherapy can be used.
MATERIALS AND METHODS
In this Ethics Approved Study, databases of the Long Term Follow-Up Clinic at Sydney Children's Hospital and the Prince of Wales Cancer Centre were audited for patients who received radiotherapy to the head as a child, and subsequently developed an intracranial meningioma. Features noted were, initial diagnosis, extent of prior treatment, dose, latency to diagnosis, subsequent treatment, and outcome.
RESULTS
There were 18 patients with an equal gender mix of males/females (9), the majority of patients being treated with whole brain radiotherapy for leukaemia prophylaxis. 6 patients had radiotherapy, 4 had follow-up out to 17 years with no further adverse event, and control of the meningioma.
CONCLUSION
Surgery may still be the treatment of choice, however where appropriate radiotherapy can be considered, with good prospect of benefit to the patient.
目的
评估与放射性相关脑膜瘤（RAM）相关的情况，以及是否可以使用重复放疗。
材料与方法
在这项经伦理批准的研究中，对悉尼儿童医院长期随访诊所和威尔士亲王癌症中心的数据库进行了审核，以查找儿童时期接受过头颅放疗且随后发生颅内脑膜瘤的患者。记录的特征包括初始诊断、既往治疗范围、剂量、诊断潜伏期、后续治疗及结果。
结果
有18例患者，男女比例相等（各9例），大多数患者因预防白血病接受全脑放疗。6例患者接受了放疗，4例随访至17年无进一步不良事件，脑膜瘤得到控制。
结论
手术可能仍是首选治疗方法，不过在适当情况下可考虑放疗，有望给患者带来益处。
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