Kim Eun-Young, Murovic Judith A, Gibbs Iris C, Shuer Lawrence M, Chang Steven D
Department of Neurosurgery, Gachon University Gil Hospital, Incheon South Korea.
Department of Neurosurgery, Stanford University Medical Center, Stanford, California USA.
J Radiosurg SBRT. 2012;1(4):333-337.
Giant cell tumors (GCTs) developing from the cranial bones are rare. Occurrence of these tumors in the vicinity of eloquent areas precludes complete excision. Fractionated external beam radiotherapy (FEBRT) has been used for those cases, but with inconsistent outcomes. The authors report a case of a patient with a GCT involving the left occiput which was successfully treated by CyberKnife stereotactic radiosurgery (CK RS). There was improvement in the neurological deficit and occipital pain without adjunctive treatment. This is the first report of stereotactic radiosurgery (SRS) adopted as a primary treatment modality for a cranial GCT.
起源于颅骨的骨巨细胞瘤(GCTs)较为罕见。这些肿瘤发生在功能区附近,无法进行完整切除。对于这些病例,已采用分次外照射放疗(FEBRT),但效果不一。作者报告了1例左枕骨骨巨细胞瘤患者,通过射波刀立体定向放射外科手术(CK RS)成功治疗。在未进行辅助治疗的情况下,神经功能缺损和枕部疼痛均有改善。这是首例将立体定向放射外科手术(SRS)作为颅骨骨巨细胞瘤主要治疗方式的报告。