一名鼻咽癌患者因局部复发接受立体定向体部放疗（SBRT）再照射，每周两次治疗，出现颈动脉破裂。
Carotid blowout in a patient with nasopharyngeal carcinoma treated with SBRT re-irradiation for local recurrence using twice weekly treatment.
作者信息
Woody Neil M, Bricker Aliye, Joshi Nikhil, Zakem Sara J, Greer Matthew D, Mattson Diana, Koyfman Shlomo A
机构信息
Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, Ohio, USA.
出版信息
J Radiosurg SBRT. 2015;3(4):325-329.
Abstract
We present the case of a patient undergoing reirradiation for a T4 nasopharyngeal tumor 1 year after his initial radiation, treated with SBRT to a moderate dose with twice weekly fractionation. Despite the measures of caution employed, the patient had a fatal carotid blowout at 7 months following SBRT. This suggests that spacing apart fractions of SBRT alone may not be sufficient to obviate the risk of carotid blowout syndrome and other risk factors and interventions should be considered.
摘要
我们报告了一例患者，其在初次放疗1年后因T4期鼻咽癌接受再程放疗，采用立体定向体部放疗（SBRT）至中等剂量，每周分两次进行。尽管采取了谨慎措施，但该患者在SBRT后7个月出现致命性颈动脉破裂。这表明，单纯增加SBRT分割次数可能不足以消除颈动脉破裂综合征的风险，应考虑其他风险因素及干预措施。
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