• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名鼻咽癌患者因局部复发接受立体定向体部放疗(SBRT)再照射,每周两次治疗,出现颈动脉破裂。

Carotid blowout in a patient with nasopharyngeal carcinoma treated with SBRT re-irradiation for local recurrence using twice weekly treatment.

作者信息

Woody Neil M, Bricker Aliye, Joshi Nikhil, Zakem Sara J, Greer Matthew D, Mattson Diana, Koyfman Shlomo A

机构信息

Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

J Radiosurg SBRT. 2015;3(4):325-329.

PMID:29296415
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5675500/
Abstract

We present the case of a patient undergoing reirradiation for a T4 nasopharyngeal tumor 1 year after his initial radiation, treated with SBRT to a moderate dose with twice weekly fractionation. Despite the measures of caution employed, the patient had a fatal carotid blowout at 7 months following SBRT. This suggests that spacing apart fractions of SBRT alone may not be sufficient to obviate the risk of carotid blowout syndrome and other risk factors and interventions should be considered.

摘要

我们报告了一例患者,其在初次放疗1年后因T4期鼻咽癌接受再程放疗,采用立体定向体部放疗(SBRT)至中等剂量,每周分两次进行。尽管采取了谨慎措施,但该患者在SBRT后7个月出现致命性颈动脉破裂。这表明,单纯增加SBRT分割次数可能不足以消除颈动脉破裂综合征的风险,应考虑其他风险因素及干预措施。

相似文献

1
Carotid blowout in a patient with nasopharyngeal carcinoma treated with SBRT re-irradiation for local recurrence using twice weekly treatment.一名鼻咽癌患者因局部复发接受立体定向体部放疗(SBRT)再照射,每周两次治疗,出现颈动脉破裂。
J Radiosurg SBRT. 2015;3(4):325-329.
2
Carotid Dosimetry and the Risk of Carotid Blowout Syndrome After Reirradiation With Head and Neck Stereotactic Body Radiation Therapy.颈动脉剂量学与头颈部立体定向体部放射治疗后再照射后发生颈动脉破裂综合征的风险。
Int J Radiat Oncol Biol Phys. 2018 May 1;101(1):195-200. doi: 10.1016/j.ijrobp.2017.11.045. Epub 2017 Dec 5.
3
Carotid blowout syndrome in pharyngeal cancer patients treated by hypofractionated stereotactic re-irradiation using CyberKnife: A multi-institutional matched-cohort analysis.采用 CyberKnife 行低分割立体定向再放疗治疗的咽癌患者的颈动脉破裂综合征:多机构匹配队列分析。
Radiother Oncol. 2015 Apr;115(1):67-71. doi: 10.1016/j.radonc.2015.02.021. Epub 2015 Mar 28.
4
Postirradiated carotid blowout syndrome in patients with nasopharyngeal carcinoma: a case-control study.鼻咽癌患者放疗后颈动脉破裂综合征:一项病例对照研究。
Head Neck. 2015 Jun;37(6):794-9. doi: 10.1002/hed.23671. Epub 2014 Jun 19.
5
Risk of carotid blowout after reirradiation of the head and neck: a systematic review.头颈部再放疗后颈动脉破裂风险:系统评价。
Int J Radiat Oncol Biol Phys. 2012 Mar 1;82(3):1083-9. doi: 10.1016/j.ijrobp.2010.08.029. Epub 2011 May 5.
6
Dose-response modeling the risk of carotid bleeding events after stereotactic body radiation therapy for previously irradiated head and neck cancer.剂量反应模型:立体定向体部放射治疗既往接受过放疗的头颈癌后颈动脉出血事件的风险
J Radiosurg SBRT. 2019;6(2):83-89.
7
Frequency, outcome and prognostic factors of carotid blowout syndrome after hypofractionated re-irradiation of head and neck cancer using CyberKnife: a multi-institutional study.采用 CyberKnife 对头颈部癌症进行分次再照射后颈动脉破裂综合征的频率、结果和预后因素:一项多机构研究。
Radiother Oncol. 2013 Jun;107(3):305-9. doi: 10.1016/j.radonc.2013.05.005. Epub 2013 Jun 7.
8
Stereotactic body radiotherapy for recurrent head and neck cancer: A critical review.立体定向体部放射治疗复发性头颈癌:一项批判性综述。
Head Neck. 2017 Mar;39(3):595-601. doi: 10.1002/hed.24633. Epub 2016 Dec 20.
9
[Stereotactic irradiation in head and neck cancers].[头颈部癌症的立体定向放射治疗]
Cancer Radiother. 2014 Jul-Aug;18(4):280-96. doi: 10.1016/j.canrad.2014.03.013. Epub 2014 Jul 22.
10
Safety and efficacy of hypofractionated stereotactic body reirradiation in head and neck cancer: Long-term follow-up of a large series.头颈部癌超分割立体定向体部再照射的安全性和有效性:大型系列的长期随访
Head Neck. 2015 Oct;37(10):1403-9. doi: 10.1002/hed.23763. Epub 2014 Sep 25.

引用本文的文献

1
Retrospective analysis of massive epistaxis and pseudoaneurysms in nasopharyngeal carcinoma after radiotherapy.鼻咽癌放疗后大出血及假性动脉瘤的回顾性分析
Eur Arch Otorhinolaryngol. 2022 Jun;279(6):2973-2980. doi: 10.1007/s00405-021-07111-x. Epub 2021 Oct 8.

本文引用的文献

1
Covered Stents for the Prevention and Treatment of Carotid Blowout Syndrome.用于预防和治疗颈动脉破裂综合征的覆膜支架
Neurosurgery. 2015 Aug;77(2):164-7. doi: 10.1227/NEU.0000000000000738.
2
A prospective phase 2 trial of reirradiation with stereotactic body radiation therapy plus cetuximab in patients with previously irradiated recurrent squamous cell carcinoma of the head and neck.一项关于立体定向体部放射治疗联合西妥昔单抗对先前接受过放疗的头颈部复发性鳞状细胞癌患者进行再照射的前瞻性2期试验。
Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):480-8. doi: 10.1016/j.ijrobp.2014.11.023. Epub 2015 Jan 30.
3
Carotid blowout in patients with head and neck cancer: associated factors and treatment outcomes.头颈部癌患者的颈动脉破裂:相关因素及治疗结果
Head Neck. 2015 Feb;37(2):265-72. doi: 10.1002/hed.23590. Epub 2014 Mar 20.
4
A simple strategy to decrease fatal carotid blowout syndrome after stereotactic body reirradiaton for recurrent head and neck cancers.一种降低头颈部复发性肿瘤立体定向体部再放疗后致命性颈动脉破裂综合征的简单策略。
Radiat Oncol. 2013 Oct 18;8:242. doi: 10.1186/1748-717X-8-242.
5
Examining tumor control and toxicity after stereotactic body radiotherapy in locally recurrent previously irradiated head and neck cancers: implications of treatment duration and tumor volume.立体定向体部放射治疗局部复发性既往接受过放疗的头颈癌后的肿瘤控制和毒性研究:治疗持续时间和肿瘤体积的影响
Head Neck. 2014 Sep;36(9):1349-55. doi: 10.1002/hed.23462. Epub 2014 Jan 13.
6
Frequency, outcome and prognostic factors of carotid blowout syndrome after hypofractionated re-irradiation of head and neck cancer using CyberKnife: a multi-institutional study.采用 CyberKnife 对头颈部癌症进行分次再照射后颈动脉破裂综合征的频率、结果和预后因素:一项多机构研究。
Radiother Oncol. 2013 Jun;107(3):305-9. doi: 10.1016/j.radonc.2013.05.005. Epub 2013 Jun 7.
7
Retreatment of recurrent head and neck cancer in a previously irradiated field.复发性头颈部癌症的再治疗:既往照射野内。
Semin Radiat Oncol. 2012 Jul;22(3):214-9. doi: 10.1016/j.semradonc.2012.03.006.
8
Endovascular management of carotid blowout.颈动脉破裂的血管内治疗。
World Neurosurg. 2012 Jul;78(1-2):109-14. doi: 10.1016/j.wneu.2011.08.024. Epub 2011 Nov 7.
9
Covered stents safely utilized to prevent catastrophic hemorrhage in patients with advanced head and neck malignancy.覆膜支架安全用于预防晚期头颈部恶性肿瘤患者发生灾难性出血。
J Neurointerv Surg. 2012 Nov;4(6):426-34. doi: 10.1136/neurintsurg-2011-010083. Epub 2011 Oct 7.
10
Management of vascular complications of head and neck cancer.
J Laryngol Otol. 2012 Feb;126(2):111-5. doi: 10.1017/S0022215111002416. Epub 2011 Sep 5.