颊上皮细胞显示出体细胞性的、源自骨髓的突变。
Buccal epithelial cells display somatic, bone marrow-derived mutation.
作者信息
Gilles Scott R, Baughn Linda B, Schomaker Matthew L, Courville Elizabeth L, Nelson Andrew C, Sachs Zohar
机构信息
Department of Laboratory Medicine and Pathology, University of Minnesota Medical Center Fairview, Minneapolis, MN.
Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
出版信息
Blood Adv. 2017 Nov 16;1(25):2302-2306. doi: 10.1182/bloodadvances.2017012229. eCollection 2017 Nov 28.
Abstract
Buccal epithelial cells harbor an MPN-associated mutation in a patient with -mutant essential thrombocytosis, Ph CML, and no germ line mutation.
摘要
在一名患有JAK2突变型原发性血小板增多症、Ph阳性慢性粒细胞白血病且无胚系突变的患者中，颊黏膜上皮细胞存在一种与骨髓增殖性肿瘤相关的突变。
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