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胸膜腹膜分流术在镰状细胞病中与中心静脉导管相关血栓形成所致乳糜胸的应用

Use of Pleuroperitoneal Shunt in Chylothorax Related to Central Line Associated Thrombosis in Sickle Cell Disease.

作者信息

Spiwak Elizabeth, Wiesenauer Chad, Panigrahi Arun, Raj Ashok

机构信息

Department of Pediatrics, University of Louisecille, Louisville, KY 40202, USA.

Department of Pediatric Surgery, University of Louisville, Louisville, KY 40202, USA.

出版信息

Children (Basel). 2018 Jan 2;5(1):7. doi: 10.3390/children5010007.

DOI:10.3390/children5010007
PMID:29301288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5789289/
Abstract

Central vein thrombosis as a cause of chylothorax is uncommon, and in a few cases in the literature was related to thrombotic complications of central venous access devices (CVAD). Superior vena cava (SVC) occlusion-induced chylothorax has been described in adult sickle cell disease (SCD) in a setting of chronic indwelling CVAD. There are limited reports on chylothorax induced by central venous thrombosis secondary to chronic CVAD in children with SCD. We describe an 8-year-old male patient, with a history of SCD, maintained on long term erythrocytapheresis for primary prevention of stroke, and whose clinical course was complicated by chylothorax which was successfully treated with a pleuroperitoneal shunt.

摘要

中心静脉血栓形成作为乳糜胸的病因并不常见,文献中的少数病例与中心静脉通路装置(CVAD)的血栓形成并发症有关。上腔静脉(SVC)闭塞引起的乳糜胸已在成年镰状细胞病(SCD)伴有慢性留置CVAD的情况下被描述。关于SCD儿童慢性CVAD继发中心静脉血栓形成所致乳糜胸的报道有限。我们描述了一名8岁男性患者,有SCD病史,长期接受红细胞单采术以预防中风,其临床病程因乳糜胸而复杂化,该乳糜胸通过胸膜腹膜分流术成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/7ea5ff5dac5f/children-05-00007-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/10887ca50287/children-05-00007-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/fa71cf1523a4/children-05-00007-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/b4aca3692f3e/children-05-00007-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/92626b9d4b23/children-05-00007-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/134777af1d48/children-05-00007-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/53143d16fa04/children-05-00007-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/7ea5ff5dac5f/children-05-00007-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/10887ca50287/children-05-00007-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/fa71cf1523a4/children-05-00007-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/b4aca3692f3e/children-05-00007-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/92626b9d4b23/children-05-00007-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/134777af1d48/children-05-00007-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/53143d16fa04/children-05-00007-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2280/5789289/7ea5ff5dac5f/children-05-00007-g007.jpg

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本文引用的文献

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Innovative Use of Denver Shunt in a Child with Generalized Lymphatic Anomaly.
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Interventional radiologic placement of Denver pleuroperitoneal shunt for refractory chylothorax.丹佛胸腹分流术经介入放射学方法置入治疗难治性乳糜胸
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Venous thromboembolism in cystic fibrosis.囊性纤维化中的静脉血栓栓塞症。
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The use of pleuroperitoneal shunts in the management of persistent chylothorax in infants.胸膜腹膜分流术在婴儿持续性乳糜胸治疗中的应用。
J Pediatr Surg. 1999 Feb;34(2):286-90. doi: 10.1016/s0022-3468(99)90192-6.