Pol B, Brandone J M, Le Treut Y P, Bricot R
Ann Chir. 1989;43(1):68-72.
We report a series of 413 patients with colo-rectal adenocarcinoma. 328 had a curative resection and 277 of them had elective lymphadenectomy; 51 had no lymphadenectomy because of either age or poor general status. Operative morbidity and mortality were not increased by lymphadenectomy. Survival was related to the lymph node involvement: 70.6% 5 year survival in patients without lymph node metastases, 49.3% 5 year survival in patients with lymph node metastases (P less than 0.001). However lymphadenectomy did not affect the survival rate of the patients. We conclude that lymphadenectomy had no deleterious effect. However, its real benefit on long term survival must be evaluated in further prospective randomised studies.
我们报告了一组413例结肠直肠癌患者。328例行根治性切除术,其中277例行选择性淋巴结清扫术;51例因年龄或全身状况差未行淋巴结清扫术。淋巴结清扫术并未增加手术 morbidity 和 mortality。生存率与淋巴结受累情况相关:无淋巴结转移患者的5年生存率为70.6%,有淋巴结转移患者的5年生存率为49.3%(P<0.001)。然而,淋巴结清扫术并未影响患者的生存率。我们得出结论,淋巴结清扫术没有有害影响。然而,其对长期生存的实际益处必须在进一步的前瞻性随机研究中进行评估。