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欧洲动脉粥样硬化预防调查:心血管疾病预防的经验教训

The EUROASPIRE surveys: lessons learned in cardiovascular disease prevention.

作者信息

Kotseva Kornelia

机构信息

National Heart & Lung Institute, Imperial College London, London, UK.

Department of Public Health, University of Ghent, Ghent, Belgium.

出版信息

Cardiovasc Diagn Ther. 2017 Dec;7(6):633-639. doi: 10.21037/cdt.2017.04.06.

Abstract

The Joint European Societies (JES) guidelines on cardiovascular disease (CVD) prevention published in 1994, 1998, 2003, 2007, 2012 and 2016 defined lifestyle and risk factors targets for patients with coronary or other atherosclerotic disease and people at high risk of developing CVD. Guideline implementation in Europe has been evaluated with four cross-sectional EUROASPIRE surveys starting in mid-1990s. The results showed poor lifestyle and risk factor management in patients with CHD and in high CVD risk people with high prevalences of smoking, obesity, central obesity and diabetes. The control of blood pressure, lipids and glucose was far from optimal. A comparison across the recent three surveys provided a unique description of time trends for secondary prevention over a period of 14 years. The results showed adverse lifestyle trends, a substantial increase in obesity, central obesity and diabetes. Despite significant improvement of blood pressure and lipid control many patients were not reaching the risk factor goals and there was no change in glucose control. Comparing the most recent two surveys, there were no major differences in lifestyle and risk factor management in people at high risk of developing CVD. A new approach to CVD prevention integrating primary and secondary prevention into a modern preventive cardiology programme, focusing on lifestyle and risk factor management is required, in order to reduce the risk of CVD events and improve quality of life in patients with CHD and those at high risk of developing CVD.

摘要

欧洲联合学会(JES)于1994年、1998年、2003年、2007年、2012年和2016年发布的心血管疾病(CVD)预防指南,为冠心病或其他动脉粥样硬化疾病患者以及有发生CVD高风险的人群确定了生活方式和风险因素目标。自20世纪90年代中期开始,通过四项横断面EUROASPIRE调查对欧洲的指南实施情况进行了评估。结果显示,冠心病患者以及有高CVD风险的人群生活方式和风险因素管理较差,吸烟、肥胖、中心性肥胖和糖尿病的患病率较高。血压、血脂和血糖的控制远未达到最佳状态。对最近三项调查的比较提供了对14年期间二级预防时间趋势的独特描述。结果显示生活方式出现不良趋势,肥胖、中心性肥胖和糖尿病大幅增加。尽管血压和血脂控制有显著改善,但许多患者仍未达到风险因素目标,血糖控制也没有变化。比较最近的两项调查,有发生CVD高风险人群的生活方式和风险因素管理没有重大差异。需要一种新的CVD预防方法,将一级预防和二级预防整合到现代预防性心脏病学计划中,重点是生活方式和风险因素管理,以降低CVD事件的风险并改善冠心病患者和有发生CVD高风险人群的生活质量。

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