Cheung K L, Evers S M A A, De Vries H, Levy P, Pokhrel S, Jones T, Danner M, Wentlandt J, Knufinke L, Mayer S, Hiligsmann M
a Department of Health Services Research , Care and Public Health Research Institute (CAPHRI), Maastricht University , Maastricht , Netherlands.
b Department of Health Promotion , Care and Public Health Research Institute (CAPHRI), Maastricht University , Maastricht , Netherlands.
Expert Rev Pharmacoecon Outcomes Res. 2018 Jun;18(3):297-304. doi: 10.1080/14737167.2018.1421459. Epub 2018 Jan 5.
To enhance usage of health technology assessment (HTA) in decision-making, it is important to prioritise important barriers and facilitators to the uptake of HTA. This study aims to quantify and compare the relative importance of barriers and facilitators regarding the use of HTA in several European countries.
A survey containing two best-worst scaling (BWS) object case studies (i.e. barriers and facilitators) were conducted among 136 policy makers and HTA researchers from the Netherlands, Germany, France, and United Kingdom. Hierarchical Bayes analysis generated the mean relative importance score (RIS) for each factor and subgroup analyses assessed differences between countries.
Six barriers (RIS≥5) and five facilitators (RIS≥6) were deemed highly important. Eleven barriers and ten facilitators differed in their importance between countries. Policy characteristics, research & researcher characteristics, and organisation & resources were particularly important to facilitate uptake of HTA, such as an explicit framework for decision-making and research of sufficient quality.
The most paramount barriers and facilitators to HTA usage were quantified. For all countries it is crucial to create an explicit framework for the decision-making context to include HTA evidence. Country differences in the quality of research emphasize the need for enhanced international collaboration in HTA.
为了提高卫生技术评估（HTA）在决策中的应用，确定影响HTA采用的重要障碍和促进因素至关重要。本研究旨在量化并比较几个欧洲国家在HTA使用方面障碍和促进因素的相对重要性。
对来自荷兰、德国、法国和英国的136名政策制定者和HTA研究人员进行了一项调查，其中包含两个最佳-最差尺度（BWS）对象案例研究（即障碍和促进因素）。分层贝叶斯分析得出每个因素的平均相对重要性得分（RIS）, 亚组分析评估了各国之间的差异。
六个障碍（RIS≥5）和五个促进因素（RIS≥6）被认为非常重要。11个障碍和10个促进因素在各国之间的重要性存在差异。政策特征、研究及研究人员特征以及组织与资源对于促进HTA的采用尤为重要，例如明确的决策框架和高质量的研究。
量化了HTA使用中最重要的障碍和促进因素。对所有国家来说，创建一个明确的决策背景框架以纳入HTA证据至关重要。各国研究质量的差异强调了加强HTA国际合作的必要性。
